Control of lysosomal-mediated cell death by the pH-dependent calcium channel RECS1

Programmed cell death is regulated by the balance between activating and inhibitory signals. Here, we have identified RECS1 (responsive to centrifugal force and shear stress 1) [also known as TMBIM1 (transmembrane BAX inhibitor motif containing 1)] as a proapoptotic member of the TMBIM family. In co...

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Detalles Bibliográficos
Autores principales: Pihán, Philippe, Lisbona, Fernanda, Borgonovo, Janina, Edwards-Jorquera, Sandra, Nunes-Hasler, Paula, Castillo, Karen, Kepp, Oliver, Urra, Hery, Saarnio, Suvi, Vihinen, Helena, Carreras-Sureda, Amado, Forveille, Sabrina, Sauvat, Allan, De Giorgis, Daniela, Pupo, Amaury, Rodríguez, Diego A., Quarato, Giovanni, Sagredo, Alfredo, Lourido, Fernanda, Letai, Anthony, Latorre, Ramon, Kroemer, Guido, Demaurex, Nicolas, Jokitalo, Eija, Concha, Miguel L., Glavic, Álvaro, Green, Douglas R., Hetz, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589314/
https://www.ncbi.nlm.nih.gov/pubmed/34767445
http://dx.doi.org/10.1126/sciadv.abe5469

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