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PEPT1 is essential for the growth of pancreatic cancer cells: a viable drug target

PEPT1 is a proton-coupled peptide transporter that is up-regulated in PDAC cell lines and PDXs, with little expression in the normal pancreas. However, the relevance of this up-regulation to cancer progression and the mechanism of up-regulation have not been investigated. Herein, we show that PEPT1...

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Detalles Bibliográficos
Autores principales:	Schniers, Bradley K., Rajasekaran, Devaraja, Korac, Ksenija, Sniegowski, Tyler, Ganapathy, Vadivel, Bhutia, Yangzom D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Cancer
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589330/ https://www.ncbi.nlm.nih.gov/pubmed/34569600 http://dx.doi.org/10.1042/BCJ20210377

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