Cargando…
BACH1, the master regulator of oxidative stress, has a dual effect on CFTR expression
The cystic fibrosis transmembrane conductance regulator (CFTR) gene lies within a topologically associated domain (TAD) in which multiple cis-regulatory elements (CREs) and transcription factors (TFs) regulate its cell-specific expression. The CREs are recruited to the gene promoter by a looping mec...
Autores principales: | NandyMazumdar, Monali, Paranjapye, Alekh, Browne, James, Yin, Shiyi, Leir, Shih-Hsing, Harris, Ann |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589331/ https://www.ncbi.nlm.nih.gov/pubmed/34605540 http://dx.doi.org/10.1042/BCJ20210252 |
Ejemplares similares
-
Looping of upstream cis-regulatory elements is required for CFTR expression in human airway epithelial cells
por: NandyMazumdar, Monali, et al.
Publicado: (2020) -
Krüppel-like factor 5 regulates wound repair and the innate immune response in human airway epithelial cells
por: Paranjapye, Alekh, et al.
Publicado: (2021) -
Cross-talk between enhancers, structural elements and activating transcription factors maintains the 3D architecture and expression of the CFTR gene
por: Yin, Shiyi, et al.
Publicado: (2022) -
Cell function and identity revealed by comparative scRNA-seq analysis in human nasal, bronchial and epididymis epithelia
por: Paranjapye, Alekh, et al.
Publicado: (2022) -
A functional genomics approach to investigate the differentiation of iPSCs into lung epithelium at air‐liquid interface
por: Kerschner, Jenny L., et al.
Publicado: (2020)