Cargando…

TIM‐3 as a potential exhaustion marker in CD4(+) T cells of COVID‐19 patients

BACKGROUND: COVID‐19 causes a range of clinical symptoms from mild to critical and can be life‐threatening. Up to now, it has led to many deaths. We aimed to evaluate exhausted markers on CD4(+) T cells of COVID‐19 patients. METHODS: In this study, we evaluated 44 patients with confirmed COVID‐19 di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Modabber, Zahra, Shahbazi, Mehdi, Akbari, Roghayeh, Bagherzadeh, Mojgan, Firouzjahi, Alireza, Mohammadnia‐Afrouzi, Mousa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589347/ https://www.ncbi.nlm.nih.gov/pubmed/34499819 http://dx.doi.org/10.1002/iid3.526

Ejemplares similares

Pronounce expression of Tim-3 and CD39 but not PD1 defines CD8 T cells in critical Covid-19 patients
por: Shahbazi, Mehdi, et al.
Publicado: (2021)

Increased Levels of serum Pentraxin 3 in Critical Coronavirus Disease-2019 Patients
por: Moulana, Zahra, et al.
Publicado: (2021)

Soluble CD30, the Immune Response, and Acute Rejection in Human Kidney Transplantation: A Systematic Review and Meta-Analysis
por: Mirzakhani, Mohammad, et al.
Publicado: (2020)

The association of decreased HLA-G(+) immune cell frequencies with critical COVID-19 patients
por: Ramzannezhad, Somayeh, et al.
Publicado: (2022)

Vitamin D receptor expression in sperm of males with unexplained infertility
por: Akbari Sagheb, Zahra, et al.
Publicado: (2023)

Female Unexplained Infertility: A Disease with Imbalanced Adaptive Immunity
por: Ehsani, Motahareh, et al.
Publicado: (2019)

Editorial: The Spectrum of Treg Subsets in Transplantation: Immune Regulation and Tolerance Induction
por: Mohammadnia-Afrouzi, Mousa, et al.
Publicado: (2022)

Expression of PD-1 and Tim-3 markers of T-cell exhaustion is associated with CD4 dynamics during the course of untreated and treated HIV infection
por: Rallón, Norma, et al.
Publicado: (2018)

Tim-3 Negatively Regulates Cytotoxicity in Exhausted CD8(+) T Cells in HIV Infection
por: Sakhdari, Ali, et al.
Publicado: (2012)

Genetic Mutations of Tim-3 Ligand and Exhausted Tim-3(+) CD8(+) T Cells and Survival in Diffuse Large B Cell Lymphoma
por: Zhang, Tingting, et al.
Publicado: (2020)

Corrigendum to “Genetic Mutations of Tim-3 Ligand and Exhausted Tim-3(+) CD8(+) T Cells and Survival in Diffuse Large B Cell Lymphoma”
por: Zhang, Tingting, et al.
Publicado: (2021)

TIM-3(+) T cells are not exhausted but activated cells in the tumor microenvironment
por: Jie, Hyun-Bae, et al.
Publicado: (2013)

Transcriptomic Profiling of Tumor-Infiltrating CD4(+)TIM-3(+) T Cells Reveals Their Suppressive, Exhausted, and Metastatic Characteristics in Colorectal Cancer Patients
por: Sasidharan Nair, Varun, et al.
Publicado: (2020)

Characterization of age‐associated exhausted CD8(+) T cells defined by increased expression of Tim‐3 and PD‐1
por: Lee, Kyoo‐A, et al.
Publicado: (2016)

TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection
por: Jayaraman, Pushpa, et al.
Publicado: (2016)

Long non-coding RNA Lnc-Tim3 exacerbates CD8 T cell exhaustion via binding to Tim-3 and inducing nuclear translocation of Bat3 in HCC
por: Ji, Jie, et al.
Publicado: (2018)

Distinct prognostic value of circulating anti-telomerase CD4(+) Th1 immunity and exhausted PD-1(+)/TIM-3(+) T cells in lung cancer
por: Laheurte, Caroline, et al.
Publicado: (2019)

Posttreatment Downregulation of Type III Interferons in Patients with Acute Brucellosis
por: Shokri, Mehran, et al.
Publicado: (2021)

Phosphatidylserine-Induced Conformational Modulation of Immune Cell Exhaustion-Associated Receptor TIM3
por: Weber, Jeffrey K., et al.
Publicado: (2017)

Mertk Interacts with Tim-4 to Enhance Tim-4-Mediated Efferocytosis
por: Moon, Byeongjin, et al.
Publicado: (2020)

Mast cell activation is enhanced by Tim1:Tim4 interaction but not by Tim-1 antibodies
por: Phong, Binh, et al.
Publicado: (2016)

Inhibition of Exosome Release Sensitizes U937 Cells to PEGylated Liposomal Doxorubicin
por: Hekmatirad, Shirin, et al.
Publicado: (2021)

Exhaustion of CD4+ T-cells mediated by the Kynurenine Pathway in Melanoma
por: Rad Pour, Soudabeh, et al.
Publicado: (2019)

CD8(+) T cells exhaustion induced by myeloid‐derived suppressor cells in myelodysplastic syndromes patients might be through TIM3/Gal‐9 pathway
por: Tao, Jinglian, et al.
Publicado: (2019)

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
por: Sakuishi, Kaori, et al.
Publicado: (2011)

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
por: Sakuishi, Kaori, et al.
Publicado: (2010)

Upregulation of the Tim-3/Galectin-9 Pathway of T Cell Exhaustion in Chronic Hepatitis B Virus Infection
por: Nebbia, Gaia, et al.
Publicado: (2012)

Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion
por: Zhu, Chen, et al.
Publicado: (2021)

The Binding Properties of Glycosylated and Non-Glycosylated Tim-3 Molecules on CD4(+)CD25(+) T Cells
por: Lee, Mi Jin, et al.
Publicado: (2009)

Tissue-resident macrophages in the intestine are long lived and defined by Tim-4 and CD4 expression
por: Shaw, Tovah N., et al.
Publicado: (2018)

Differential expression of PD-1 and Tim-3 marks activation versus exhaustion status of T cells in the tumor microenvironment
por: Li, Jing, et al.
Publicado: (2014)

Acute myeloid leukemia stem cell markers in prognosis and targeted therapy: potential impact of BMI-1, TIM-3 and CLL-1
por: Darwish, Noureldien H.E., et al.
Publicado: (2016)

A Rare Case of Cardiac Metastasis from Colon Cancer
por: Modabber, Zahra, et al.
Publicado: (2022)

Increased PD-1+Tim-3+ exhausted T cells in bone marrow may influence the clinical outcome of patients with AML
por: Tan, Jiaxiong, et al.
Publicado: (2020)

CXCR5 and TIM-3 expressions define distinct exhausted T cell subsets in experimental cutaneous infection with Leishmania mexicana
por: Diupotex, Mariana, et al.
Publicado: (2023)

Influenza Vaccination and Guillain–Barré Syndrome: Reality or Fear
por: Babazadeh, Arefeh, et al.
Publicado: (2019)

Seroprevalence Estimates of Latent and Acute Toxoplasma Infections in HIV(+) People—Call for Action in Underprivileged Communities
por: Rostami, Ali, et al.
Publicado: (2021)

Filarial Lymphedema Patients Are Characterized by Exhausted CD4(+) T Cells
por: Horn, Sacha, et al.
Publicado: (2022)

CD39(+) conventional CD4(+) T cells with exhaustion traits and cytotoxic potential infiltrate tumors and expand upon CTLA-4 blockade
por: Bossio, Sabrina N., et al.
Publicado: (2023)

Highly expression of Tim-3 on HIV-specific T cells associated with disease progression and T-cell exhaustion in HIV-1 infected Chinese
por: Liu, Z, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_o81m3i005i2aqna5r7q59jvicv