NOD/scid IL‐2Rγ(null) mice reconstituted with peripheral blood mononuclear cells from patients with Crohn's disease reflect the human pathological phenotype

INTRODUCTION: Crohn's disease (CD) is characterized by pronounced intestinal fibrosis and severe mucosal damage and conventional animal models are limited to reflect these pathological manifestations. The aim of this study was to examine whether the combination of patient immune‐profiling and p...

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Detalles Bibliográficos
Autores principales: Unterweger, Anna‐Lena, Rüscher, Alena, Seuß, Marietta, Winkelmann, Paula, Beigel, Florian, Koletzko, Leandra, Breiteneicher, Simone, Siebeck, Matthias, Gropp, Roswitha, Aszodi, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589348/
https://www.ncbi.nlm.nih.gov/pubmed/34499803
http://dx.doi.org/10.1002/iid3.516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589348/
https://www.ncbi.nlm.nih.gov/pubmed/34499803
http://dx.doi.org/10.1002/iid3.516

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