SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff

INTRODUCTION: One dose of a coronavirus disease 2019 (COVID‐19) vaccine can elicit high antibody titers in individuals who were previously infected by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). However, it is unclear how a SARS‐CoV‐2 infection shortly after a first COVID‐19 vaccin...

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Autores principales: Urlaub, Doris, Wolfsdorff, Natalie, Durak, Deniz, Renken, Frank, Watzl, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589355/
https://www.ncbi.nlm.nih.gov/pubmed/34499821
http://dx.doi.org/10.1002/iid3.525
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author Urlaub, Doris
Wolfsdorff, Natalie
Durak, Deniz
Renken, Frank
Watzl, Carsten
author_facet Urlaub, Doris
Wolfsdorff, Natalie
Durak, Deniz
Renken, Frank
Watzl, Carsten
author_sort Urlaub, Doris
collection PubMed
description INTRODUCTION: One dose of a coronavirus disease 2019 (COVID‐19) vaccine can elicit high antibody titers in individuals who were previously infected by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). However, it is unclear how a SARS‐CoV‐2 infection shortly after a first COVID‐19 vaccine dose affects antibody responses. METHODS: Here we investigate residents and staff of a nursing home, where a COVID‐19 outbreak occurred shortly after the first BNT162b2 immunization. RESULTS AND CONCLUSIONS: Our data show that individuals who got infected as early as 10 days after their first immunization show antibody levels comparable to fully vaccinated individuals.
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spelling pubmed-85893552021-11-19 SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff Urlaub, Doris Wolfsdorff, Natalie Durak, Deniz Renken, Frank Watzl, Carsten Immun Inflamm Dis Original Articles INTRODUCTION: One dose of a coronavirus disease 2019 (COVID‐19) vaccine can elicit high antibody titers in individuals who were previously infected by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). However, it is unclear how a SARS‐CoV‐2 infection shortly after a first COVID‐19 vaccine dose affects antibody responses. METHODS: Here we investigate residents and staff of a nursing home, where a COVID‐19 outbreak occurred shortly after the first BNT162b2 immunization. RESULTS AND CONCLUSIONS: Our data show that individuals who got infected as early as 10 days after their first immunization show antibody levels comparable to fully vaccinated individuals. John Wiley and Sons Inc. 2021-09-09 /pmc/articles/PMC8589355/ /pubmed/34499821 http://dx.doi.org/10.1002/iid3.525 Text en © 2021 The Authors. Immunity, Inflammation and Disease published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Urlaub, Doris
Wolfsdorff, Natalie
Durak, Deniz
Renken, Frank
Watzl, Carsten
SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff
title SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff
title_full SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff
title_fullStr SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff
title_full_unstemmed SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff
title_short SARS‐CoV‐2 infection shortly after BNT162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff
title_sort sars‐cov‐2 infection shortly after bnt162b2 vaccination results in high anti‐spike antibody levels in nursing home residents and staff
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589355/
https://www.ncbi.nlm.nih.gov/pubmed/34499821
http://dx.doi.org/10.1002/iid3.525
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