CCL2 produced by pancreatic ductal adenocarcinoma is essential for the accumulation and activation of monocytic myeloid‐derived suppressor cells

INTRODUCTION: The development of pancreatic ductal adenocarcinoma (PDAC) is closely tied with the immune system. C‐C motif chemokine ligands (CCL) were proved to lead to immune recruitment and training. Thus, we reckoned CCL2 to be the kernel of immune suppression in PDAC tissues. METHODS: We compar...

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Detalles Bibliográficos
Autores principales: Gu, Haitao, Deng, Wensheng, Zheng, Zhong, Wu, Ke, Sun, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589368/
https://www.ncbi.nlm.nih.gov/pubmed/34525267
http://dx.doi.org/10.1002/iid3.523

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