Cargando…
Dispatching plasma membrane cholesterol and Sonic Hedgehog dispatch: two sides of the same coin?
Vertebrate and invertebrate Hedgehog (Hh) morphogens signal over short and long distances to direct cell fate decisions during development and to maintain tissue homeostasis after birth. One of the most important questions in Hh biology is how such Hh signaling to distant target cells is achieved, b...
Autores principales: | Ehring, Kristina, Grobe, Kay |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589413/ https://www.ncbi.nlm.nih.gov/pubmed/34515747 http://dx.doi.org/10.1042/BST20210918 |
Ejemplares similares
-
Conserved cholesterol-related activities of Dispatched 1 drive Sonic hedgehog shedding from the cell membrane
por: Ehring, Kristina, et al.
Publicado: (2021) -
Cleavage activates Dispatched for Sonic Hedgehog ligand release
por: Stewart, Daniel P, et al.
Publicado: (2018) -
Cryo-EM structure of the Hedgehog release protein Dispatched
por: Cannac, Fabien, et al.
Publicado: (2020) -
Sonic hedgehog is basolaterally sorted from the TGN and transcytosed to the apical domain involving Dispatched-1 at Rab11-ARE
por: Sandoval, Lisette, et al.
Publicado: (2022) -
Architecture of Dispatched, a Transmembrane Protein Responsible for Hedgehog Release
por: Luo, Yitian, et al.
Publicado: (2021)