Probing Multivalent Carbohydrate-Protein Interactions With On-Chip Synthesized Glycopeptides Using Different Functionalized Surfaces

Multivalent ligand–protein interactions are a commonly employed approach by nature in many biological processes. Single glycan–protein interactions are often weak, but their affinity and specificity can be drastically enhanced by engaging multiple binding sites. Microarray technology allows for quic...

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Detalles Bibliográficos
Autores principales: Tsouka, Alexandra, Hoetzel, Kassandra, Mende, Marco, Heidepriem, Jasmin, Paris, Grigori, Eickelmann, Stephan, Seeberger, Peter H., Lepenies, Bernd, Loeffler, Felix F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589469/
https://www.ncbi.nlm.nih.gov/pubmed/34778215
http://dx.doi.org/10.3389/fchem.2021.766932

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