Cargando…
Downregulation of RIP3 Improves the Protective Effect of ATF6 in an Acute Liver Injury Model
BACKGROUND: Activating transcription factor 6 (ATF6) and receptor-interacting protein 3 (RIP3) are important signaling proteins in endoplasmic reticulum (ER) stress and necroptosis, respectively. However, their regulatory relationship and clinical significance are unknown. We investigate the impact...
Autores principales: | Huang, Mei-Ying, Wan, Dian-Wei, Deng, Jie, Guo, Wen-Jie, Huang, Yue, Chen, Huan, Xu, De-Lin, Jiang, Zhi-Gang, Xue, Yuan, He, Yi-Huai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589516/ https://www.ncbi.nlm.nih.gov/pubmed/34778458 http://dx.doi.org/10.1155/2021/8717565 |
Ejemplares similares
-
IL-6/STAT3 Induced Neuron Apoptosis in Hypoxia by Downregulating ATF6 Expression
por: Zhou, Simin, et al.
Publicado: (2021) -
Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury
por: Deutsch, M, et al.
Publicado: (2015) -
Roles and Clinical Significances of ATF6, EMC6, and APAF1 in Prognosis of Pancreatic Cancer
por: Xiao, Wang, et al.
Publicado: (2022) -
Feedback loop between hepatocyte nuclear factor 1α and endoplasmic reticulum stress mitigates liver injury by downregulating hepatocyte apoptosis
por: Liu, Si-Ying, et al.
Publicado: (2022) -
Catalytically inactive RIP1 and RIP3 deficiency protect against acute ischemic stroke by inhibiting necroptosis and neuroinflammation
por: Zhang, Yue, et al.
Publicado: (2020)