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Epigenetic prediction of major depressive disorder

Variation in DNA methylation (DNAm) is associated with lifestyle factors such as smoking and body mass index (BMI) but there has been little research exploring its ability to identify individuals with major depressive disorder (MDD). Using penalised regression on genome-wide CpG methylation, we test...

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Detalles Bibliográficos
Autores principales: Barbu, Miruna C., Shen, Xueyi, Walker, Rosie M., Howard, David M., Evans, Kathryn L., Whalley, Heather C., Porteous, David J., Morris, Stewart W., Deary, Ian J., Zeng, Yanni, Marioni, Riccardo E., Clarke, Toni-Kim, McIntosh, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589651/
https://www.ncbi.nlm.nih.gov/pubmed/32523041
http://dx.doi.org/10.1038/s41380-020-0808-3