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Neonatal donation: are newborns too young to be recognized?

Neonatal organ and tissue donation is not common practice in the Netherlands. At the same time, there is a transplant waiting list for small size-matched organs and tissues. Multiple factors may contribute to low neonatal donation rates, including a lack of awareness of this option. This study provi...

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Autores principales: Vileito, Alicija, Hulzebos, Christian V., Toet, Mona C., Baptist, Dyvonne H., Verhagen, Eduard A. A., Siebelink, Marion J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589733/
https://www.ncbi.nlm.nih.gov/pubmed/34105002
http://dx.doi.org/10.1007/s00431-021-04139-3
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author Vileito, Alicija
Hulzebos, Christian V.
Toet, Mona C.
Baptist, Dyvonne H.
Verhagen, Eduard A. A.
Siebelink, Marion J.
author_facet Vileito, Alicija
Hulzebos, Christian V.
Toet, Mona C.
Baptist, Dyvonne H.
Verhagen, Eduard A. A.
Siebelink, Marion J.
author_sort Vileito, Alicija
collection PubMed
description Neonatal organ and tissue donation is not common practice in the Netherlands. At the same time, there is a transplant waiting list for small size-matched organs and tissues. Multiple factors may contribute to low neonatal donation rates, including a lack of awareness of this option. This study provides insight into potential neonatal organ and tissue donors and reports on how many donors were actually reported to the procurement organization. We performed a retrospective analysis of the mortality database and medical records of two largest neonatal intensive care units (NICUs) in the Netherlands. This study reviewed records of neonates with a gestational age >37 weeks and weight >3000g who died in the period from January 1, 2005 through December 31, 2016. During the study period, 259 term-born neonates died in the two NICUs. In total, 132 neonates with general contra-indications for donation were excluded. The medical records of 127 neonates were examined for donation suitability. We identified five neonates with documented brain death who were not recognized as potential organ and/or tissue donors. Of the remaining neonates, 27 were found suitable for tissue donation. One potential tissue donor had been reported to the procurement organization. In three cases, the possibility of donation was brought up by parents. Conclusion: A low proportion (2%) of neonates who died in the NICUs were found suitable for organ donation, and a higher proportion (12%) were found suitable for tissue donation. We suggest that increased awareness concerning the possibility of neonatal donation would likely increase the identification of potential neonatal donors.
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spelling pubmed-85897332021-11-15 Neonatal donation: are newborns too young to be recognized? Vileito, Alicija Hulzebos, Christian V. Toet, Mona C. Baptist, Dyvonne H. Verhagen, Eduard A. A. Siebelink, Marion J. Eur J Pediatr Original Article Neonatal organ and tissue donation is not common practice in the Netherlands. At the same time, there is a transplant waiting list for small size-matched organs and tissues. Multiple factors may contribute to low neonatal donation rates, including a lack of awareness of this option. This study provides insight into potential neonatal organ and tissue donors and reports on how many donors were actually reported to the procurement organization. We performed a retrospective analysis of the mortality database and medical records of two largest neonatal intensive care units (NICUs) in the Netherlands. This study reviewed records of neonates with a gestational age >37 weeks and weight >3000g who died in the period from January 1, 2005 through December 31, 2016. During the study period, 259 term-born neonates died in the two NICUs. In total, 132 neonates with general contra-indications for donation were excluded. The medical records of 127 neonates were examined for donation suitability. We identified five neonates with documented brain death who were not recognized as potential organ and/or tissue donors. Of the remaining neonates, 27 were found suitable for tissue donation. One potential tissue donor had been reported to the procurement organization. In three cases, the possibility of donation was brought up by parents. Conclusion: A low proportion (2%) of neonates who died in the NICUs were found suitable for organ donation, and a higher proportion (12%) were found suitable for tissue donation. We suggest that increased awareness concerning the possibility of neonatal donation would likely increase the identification of potential neonatal donors. Springer Berlin Heidelberg 2021-06-09 2021 /pmc/articles/PMC8589733/ /pubmed/34105002 http://dx.doi.org/10.1007/s00431-021-04139-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Vileito, Alicija
Hulzebos, Christian V.
Toet, Mona C.
Baptist, Dyvonne H.
Verhagen, Eduard A. A.
Siebelink, Marion J.
Neonatal donation: are newborns too young to be recognized?
title Neonatal donation: are newborns too young to be recognized?
title_full Neonatal donation: are newborns too young to be recognized?
title_fullStr Neonatal donation: are newborns too young to be recognized?
title_full_unstemmed Neonatal donation: are newborns too young to be recognized?
title_short Neonatal donation: are newborns too young to be recognized?
title_sort neonatal donation: are newborns too young to be recognized?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589733/
https://www.ncbi.nlm.nih.gov/pubmed/34105002
http://dx.doi.org/10.1007/s00431-021-04139-3
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