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Laboratory Investigation of Preclinical Visual-Quality Metrics and Halo-Size in Enhanced Monofocal Intraocular Lenses

INTRODUCTION: This study aims to compare preclinical visual-quality metrics and halo size of intraocular lenses (IOL) with enhanced intermediate vision to a standard monofocal lens. METHODS: Three monofocal- IOL models with an extended-depth-of-focus (EDoF) intended for monocular implantation (Tecni...

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Autores principales: Łabuz, Grzegorz, Son, Hyeck-Soo, Naujokaitis, Tadas, Yildirim, Timur M., Khoramnia, Ramin, Auffarth, Gerd U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589924/
https://www.ncbi.nlm.nih.gov/pubmed/34689301
http://dx.doi.org/10.1007/s40123-021-00411-9
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author Łabuz, Grzegorz
Son, Hyeck-Soo
Naujokaitis, Tadas
Yildirim, Timur M.
Khoramnia, Ramin
Auffarth, Gerd U.
author_facet Łabuz, Grzegorz
Son, Hyeck-Soo
Naujokaitis, Tadas
Yildirim, Timur M.
Khoramnia, Ramin
Auffarth, Gerd U.
author_sort Łabuz, Grzegorz
collection PubMed
description INTRODUCTION: This study aims to compare preclinical visual-quality metrics and halo size of intraocular lenses (IOL) with enhanced intermediate vision to a standard monofocal lens. METHODS: Three monofocal- IOL models with an extended-depth-of-focus (EDoF) intended for monocular implantation (Tecnis ICB00, AE2UV/ZOE, and IsoPure) and one for monovision (RayOne EMV) were compared against a standard monofocal lens (Tecnis ZCB00). An optical-metrology station was used in the assessment of IOLs' optical quality in polychromatic light. The imaging quality was compared with metrics derived from the optical transfer function. Halo size was estimated from the projection of the point spread function under scotopic pupil. RESULTS: The monofocal IOL showed the highest image quality at the far focus. The ICB00’s, the AE2UV/ZOE’s, and the IsoPure’s performance at − 1D was superior to that of the monofocal lens. The monocular defocus tolerance of the RayOne EMV was comparable with that of the ZCB00. The RayOne EMV’s intermediate range was improved in a monovision configuration (− 1D offset). This approach, however, yielded the largest halo area, i.e., 53% of the ZCB00’s halo, compared to 34% for the IsoPure, 14% for the AE2UV/ZOE, and 8% for the ICB00. CONCLUSION: The mono-EDoF models have a clear advantage over the standard monofocal lens by expanded imaging capability beyond − 0.5D. Although the RayOne EMV provided the largest (binocular) visual-range extension, it was at the expense of monocular vision and higher susceptibility to halo. The ICB00’s and the AE2UV/ZOE’s halo-profile was similar to that of the ZCB00, indicating their low potential to induce photic phenomena. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40123-021-00411-9.
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spelling pubmed-85899242021-11-23 Laboratory Investigation of Preclinical Visual-Quality Metrics and Halo-Size in Enhanced Monofocal Intraocular Lenses Łabuz, Grzegorz Son, Hyeck-Soo Naujokaitis, Tadas Yildirim, Timur M. Khoramnia, Ramin Auffarth, Gerd U. Ophthalmol Ther Original Research INTRODUCTION: This study aims to compare preclinical visual-quality metrics and halo size of intraocular lenses (IOL) with enhanced intermediate vision to a standard monofocal lens. METHODS: Three monofocal- IOL models with an extended-depth-of-focus (EDoF) intended for monocular implantation (Tecnis ICB00, AE2UV/ZOE, and IsoPure) and one for monovision (RayOne EMV) were compared against a standard monofocal lens (Tecnis ZCB00). An optical-metrology station was used in the assessment of IOLs' optical quality in polychromatic light. The imaging quality was compared with metrics derived from the optical transfer function. Halo size was estimated from the projection of the point spread function under scotopic pupil. RESULTS: The monofocal IOL showed the highest image quality at the far focus. The ICB00’s, the AE2UV/ZOE’s, and the IsoPure’s performance at − 1D was superior to that of the monofocal lens. The monocular defocus tolerance of the RayOne EMV was comparable with that of the ZCB00. The RayOne EMV’s intermediate range was improved in a monovision configuration (− 1D offset). This approach, however, yielded the largest halo area, i.e., 53% of the ZCB00’s halo, compared to 34% for the IsoPure, 14% for the AE2UV/ZOE, and 8% for the ICB00. CONCLUSION: The mono-EDoF models have a clear advantage over the standard monofocal lens by expanded imaging capability beyond − 0.5D. Although the RayOne EMV provided the largest (binocular) visual-range extension, it was at the expense of monocular vision and higher susceptibility to halo. The ICB00’s and the AE2UV/ZOE’s halo-profile was similar to that of the ZCB00, indicating their low potential to induce photic phenomena. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40123-021-00411-9. Springer Healthcare 2021-10-24 2021-12 /pmc/articles/PMC8589924/ /pubmed/34689301 http://dx.doi.org/10.1007/s40123-021-00411-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Original Research
Łabuz, Grzegorz
Son, Hyeck-Soo
Naujokaitis, Tadas
Yildirim, Timur M.
Khoramnia, Ramin
Auffarth, Gerd U.
Laboratory Investigation of Preclinical Visual-Quality Metrics and Halo-Size in Enhanced Monofocal Intraocular Lenses
title Laboratory Investigation of Preclinical Visual-Quality Metrics and Halo-Size in Enhanced Monofocal Intraocular Lenses
title_full Laboratory Investigation of Preclinical Visual-Quality Metrics and Halo-Size in Enhanced Monofocal Intraocular Lenses
title_fullStr Laboratory Investigation of Preclinical Visual-Quality Metrics and Halo-Size in Enhanced Monofocal Intraocular Lenses
title_full_unstemmed Laboratory Investigation of Preclinical Visual-Quality Metrics and Halo-Size in Enhanced Monofocal Intraocular Lenses
title_short Laboratory Investigation of Preclinical Visual-Quality Metrics and Halo-Size in Enhanced Monofocal Intraocular Lenses
title_sort laboratory investigation of preclinical visual-quality metrics and halo-size in enhanced monofocal intraocular lenses
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589924/
https://www.ncbi.nlm.nih.gov/pubmed/34689301
http://dx.doi.org/10.1007/s40123-021-00411-9
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