The brain targeted delivery of programmed cell death 4 specific siRNA protects mice from CRS-induced depressive behavior

Depression is one of the most common psychiatric disorders. Recently, studies demonstrate that antidepressants generating BDNF not only maintain synaptic signal transmission but also repress neuroinflammatory cytokines such as IL-6 and IL-1β. Therefore, promoting BDNF expression provides a strategy...

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Detalles Bibliográficos
Autores principales: Jia, Yufeng, Zhuang, Xiao, Zhang, Yi, Zhao, Ming, Chen, Nuo, Li, Wen, Zhu, Faliang, Guo, Chun, Li, Yan, Wang, Qun, Li, Yuan, Zhang, Lining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590023/
https://www.ncbi.nlm.nih.gov/pubmed/34772918
http://dx.doi.org/10.1038/s41419-021-04361-9

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