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Image-based high-throughput mapping of TGF-β-induced phosphocomplexes at a single-cell level

Protein interactions and posttranslational modifications orchestrate cellular responses to e.g. cytokines and drugs, but it has been difficult to monitor these dynamic events in high-throughput. Here, we describe a semi-automated system for large-scale in situ proximity ligation assays (isPLA), comb...

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Detalles Bibliográficos
Autores principales:	Lönn, Peter, Al-Amin, Rasel A., Doulabi, Ehsan Manouchehri, Heldin, Johan, Gallini, Radiosa, Björkesten, Johan, Oelrich, Johan, Kamali-Moghaddam, Masood, Landegren, Ulf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590043/ https://www.ncbi.nlm.nih.gov/pubmed/34773084 http://dx.doi.org/10.1038/s42003-021-02798-4

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