Whole blood transcriptomic analysis reveals PLSCR4 as a potential marker for vaso-occlusive crises in sickle cell disease

Sickle cell disease, a common genetic blood disorder, results from a point mutation in the β-globin gene affecting the configuration of hemoglobin, predisposing to painful vaso-occlusive crisis (VOC) and multi-organ dysfunctions. There is a huge variation in the phenotypic expressions of SCD and VOC...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdulwahab, Hawra, Aljishi, Muna, Sultan, Ameera, Al-Kafaji, Ghada, Sridharan, Kannan, Bakhiet, Moiz, Taha, Safa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590045/
https://www.ncbi.nlm.nih.gov/pubmed/34772994
http://dx.doi.org/10.1038/s41598-021-01702-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590045/
https://www.ncbi.nlm.nih.gov/pubmed/34772994
http://dx.doi.org/10.1038/s41598-021-01702-8

Ejemplares similares