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Whole blood transcriptomic analysis reveals PLSCR4 as a potential marker for vaso-occlusive crises in sickle cell disease
Sickle cell disease, a common genetic blood disorder, results from a point mutation in the β-globin gene affecting the configuration of hemoglobin, predisposing to painful vaso-occlusive crisis (VOC) and multi-organ dysfunctions. There is a huge variation in the phenotypic expressions of SCD and VOC...
Autores principales: | Abdulwahab, Hawra, Aljishi, Muna, Sultan, Ameera, Al-Kafaji, Ghada, Sridharan, Kannan, Bakhiet, Moiz, Taha, Safa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590045/ https://www.ncbi.nlm.nih.gov/pubmed/34772994 http://dx.doi.org/10.1038/s41598-021-01702-8 |
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