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Stimulation of motilin secretion by bile, free fatty acids, and acidification in human duodenal organoids
OBJECTIVE: Motilin is a proximal small intestinal hormone with roles in gastrointestinal motility, gallbladder emptying, and hunger initiation. In vivo motilin release is stimulated by fats, bile, and duodenal acidification but the underlying molecular mechanisms of motilin secretion remain poorly u...
Autores principales: | Miedzybrodzka, Emily L., Foreman, Rachel E., Lu, Van B., George, Amy L., Smith, Christopher A., Larraufie, Pierre, Kay, Richard G., Goldspink, Deborah A., Reimann, Frank, Gribble, Fiona M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590067/ https://www.ncbi.nlm.nih.gov/pubmed/34662713 http://dx.doi.org/10.1016/j.molmet.2021.101356 |
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