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Stimulation of motilin secretion by bile, free fatty acids, and acidification in human duodenal organoids

OBJECTIVE: Motilin is a proximal small intestinal hormone with roles in gastrointestinal motility, gallbladder emptying, and hunger initiation. In vivo motilin release is stimulated by fats, bile, and duodenal acidification but the underlying molecular mechanisms of motilin secretion remain poorly u...

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Detalles Bibliográficos
Autores principales: Miedzybrodzka, Emily L., Foreman, Rachel E., Lu, Van B., George, Amy L., Smith, Christopher A., Larraufie, Pierre, Kay, Richard G., Goldspink, Deborah A., Reimann, Frank, Gribble, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590067/
https://www.ncbi.nlm.nih.gov/pubmed/34662713
http://dx.doi.org/10.1016/j.molmet.2021.101356

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