Rise of cGMP by partial phosphodiesterase-3A degradation enhances cardioprotection during hypoxia

3′,5′-cyclic guanosine monophosphate (cGMP) is a druggable second messenger regulating cell growth and survival in a plethora of cells and disease states, many of which are associated with hypoxia. For example, in myocardial infarction and heart failure (HF), clinical use of cGMP-elevating drugs imp...

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Detalles Bibliográficos
Autores principales: Bork, Nadja I., Kuret, Anna, Cruz Santos, Melanie, Molina, Cristina E., Reiter, Beate, Reichenspurner, Hermann, Friebe, Andreas, Skryabin, Boris V., Rozhdestvensky, Timofey S., Kuhn, Michaela, Lukowski, Robert, Nikolaev, Viacheslav O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590074/
https://www.ncbi.nlm.nih.gov/pubmed/34763298
http://dx.doi.org/10.1016/j.redox.2021.102179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590074/
https://www.ncbi.nlm.nih.gov/pubmed/34763298
http://dx.doi.org/10.1016/j.redox.2021.102179

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