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Mitochondrial DNA copy number and heteroplasmy load correlate with skeletal muscle oxidative capacity by P31 MR spectroscopy

The association between blood‐based estimates of mitochondrial DNA parameters, mitochondrial DNA copy number (mtDNA‐CN) and heteroplasmy load, with skeletal muscle bioenergetic capacity was evaluated in 230 participants of the Baltimore Longitudinal Study of Aging (mean age:74.7 years, 53% women). P...

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Detalles Bibliográficos
Autores principales: Tian, Qu, Moore, Ann Zenobia, Oppong, Richard, Ding, Jun, Zampino, Marta, Fishbein, Kenneth W., Spencer, Richard G., Ferrucci, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590093/
https://www.ncbi.nlm.nih.gov/pubmed/34612579
http://dx.doi.org/10.1111/acel.13487