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Age‐dependent integrity of the meiotic spindle assembly checkpoint in females requires Aurora kinase B
A hallmark of advanced maternal age is a significant increase in meiotic chromosome segregation errors, resulting in early miscarriages and congenital disorders. These errors most frequently occur during meiosis I (MI). The spindle assembly checkpoint (SAC) prevents chromosome segregation errors by...
Autores principales: | Blengini, Cecilia S., Nguyen, Alexandra L., Aboelenain, Mansour, Schindler, Karen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590096/ https://www.ncbi.nlm.nih.gov/pubmed/34704342 http://dx.doi.org/10.1111/acel.13489 |
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