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Age‐dependent integrity of the meiotic spindle assembly checkpoint in females requires Aurora kinase B

A hallmark of advanced maternal age is a significant increase in meiotic chromosome segregation errors, resulting in early miscarriages and congenital disorders. These errors most frequently occur during meiosis I (MI). The spindle assembly checkpoint (SAC) prevents chromosome segregation errors by...

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Detalles Bibliográficos
Autores principales: Blengini, Cecilia S., Nguyen, Alexandra L., Aboelenain, Mansour, Schindler, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590096/
https://www.ncbi.nlm.nih.gov/pubmed/34704342
http://dx.doi.org/10.1111/acel.13489

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