Monomeric C‐reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype‐dependent pattern: A risk factor for Alzheimer’s disease?

In chronic peripheral inflammation, endothelia in brain capillary beds could play a role for the apolipoprotein E4 (ApoE4)‐mediated risk for Alzheimer's disease (AD) risk. Using human brain tissues, here we demonstrate that the interactions of endothelial CD31 with monomeric C‐reactive protein...

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Detalles Bibliográficos
Autores principales: Zhang, Zhengrong, Na, Hana, Gan, Qini, Tao, Qiushan, Alekseyev, Yuriy, Hu, Junming, Yan, Zili, Yang, Jack B., Tian, Hua, Zhu, Shenyu, Li, Qiang, Rajab, Ibraheem M., Blusztajn, Jan Krizysztof, Wolozin, Benjamin, Emili, Andrew, Zhang, Xiaoling, Stein, Thor, Potempa, Lawrence A., Qiu, Wei Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590103/
https://www.ncbi.nlm.nih.gov/pubmed/34687487
http://dx.doi.org/10.1111/acel.13501

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