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When a nightmare comes true: Change in obsessive-compulsive disorder over the first months of the COVID-19 pandemic

The outbreak of the COVID-19 pandemic has particularly affected people with obsessive-compulsive disorder (OCD). Exacerbation of obsessive-compulsive symptoms (OCS) has been suspected for those with contamination-related OCD (C-OCD). However, the course of OCS over the ongoing pandemic remains uncle...

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Autores principales: Jelinek, Lena, Voderholzer, Ulrich, Moritz, Steffen, Carsten, Hannes Per, Riesel, Anja, Miegel, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590107/
https://www.ncbi.nlm.nih.gov/pubmed/34752943
http://dx.doi.org/10.1016/j.janxdis.2021.102493
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author Jelinek, Lena
Voderholzer, Ulrich
Moritz, Steffen
Carsten, Hannes Per
Riesel, Anja
Miegel, Franziska
author_facet Jelinek, Lena
Voderholzer, Ulrich
Moritz, Steffen
Carsten, Hannes Per
Riesel, Anja
Miegel, Franziska
author_sort Jelinek, Lena
collection PubMed
description The outbreak of the COVID-19 pandemic has particularly affected people with obsessive-compulsive disorder (OCD). Exacerbation of obsessive-compulsive symptoms (OCS) has been suspected for those with contamination-related OCD (C-OCD). However, the course of OCS over the ongoing pandemic remains unclear. We assessed 268 participants with OCD (n = 184 with C-OCD) in an online survey at the beginning of the pandemic in Germany, reassessing 179 participants (66.8%, 104 C-OCD) three months later. We assessed severity of OCD (OCI-R), depression (PHQ-9), experiential avoidance, as well as functional and dysfunctional beliefs. Overall, OCS and depressive symptoms did not substantially change over time. However, when people with and without C-OCD were compared, symptoms improved in patients without C-OCD (nC-OCD) but remained stable in patients with C-OCD over time. Symptom improvement was associated with male gender, higher initial OCI-R, and nC-OCD. Experiential avoidance and beliefs at the beginning of the pandemic did not generally predict change in OCS. People with OCD, particularly those with nC-OCD, showed tentative signs for signs of adapting, whereas distress in those with C-OCD remained at a high level, underlining the burden for these patients. Clinicians should be informed about how to maintain effective treatment for C-OCD during a pandemic.
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spelling pubmed-85901072021-11-15 When a nightmare comes true: Change in obsessive-compulsive disorder over the first months of the COVID-19 pandemic Jelinek, Lena Voderholzer, Ulrich Moritz, Steffen Carsten, Hannes Per Riesel, Anja Miegel, Franziska J Anxiety Disord Article The outbreak of the COVID-19 pandemic has particularly affected people with obsessive-compulsive disorder (OCD). Exacerbation of obsessive-compulsive symptoms (OCS) has been suspected for those with contamination-related OCD (C-OCD). However, the course of OCS over the ongoing pandemic remains unclear. We assessed 268 participants with OCD (n = 184 with C-OCD) in an online survey at the beginning of the pandemic in Germany, reassessing 179 participants (66.8%, 104 C-OCD) three months later. We assessed severity of OCD (OCI-R), depression (PHQ-9), experiential avoidance, as well as functional and dysfunctional beliefs. Overall, OCS and depressive symptoms did not substantially change over time. However, when people with and without C-OCD were compared, symptoms improved in patients without C-OCD (nC-OCD) but remained stable in patients with C-OCD over time. Symptom improvement was associated with male gender, higher initial OCI-R, and nC-OCD. Experiential avoidance and beliefs at the beginning of the pandemic did not generally predict change in OCS. People with OCD, particularly those with nC-OCD, showed tentative signs for signs of adapting, whereas distress in those with C-OCD remained at a high level, underlining the burden for these patients. Clinicians should be informed about how to maintain effective treatment for C-OCD during a pandemic. Elsevier Ltd. 2021-12 2021-10-30 /pmc/articles/PMC8590107/ /pubmed/34752943 http://dx.doi.org/10.1016/j.janxdis.2021.102493 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Jelinek, Lena
Voderholzer, Ulrich
Moritz, Steffen
Carsten, Hannes Per
Riesel, Anja
Miegel, Franziska
When a nightmare comes true: Change in obsessive-compulsive disorder over the first months of the COVID-19 pandemic
title When a nightmare comes true: Change in obsessive-compulsive disorder over the first months of the COVID-19 pandemic
title_full When a nightmare comes true: Change in obsessive-compulsive disorder over the first months of the COVID-19 pandemic
title_fullStr When a nightmare comes true: Change in obsessive-compulsive disorder over the first months of the COVID-19 pandemic
title_full_unstemmed When a nightmare comes true: Change in obsessive-compulsive disorder over the first months of the COVID-19 pandemic
title_short When a nightmare comes true: Change in obsessive-compulsive disorder over the first months of the COVID-19 pandemic
title_sort when a nightmare comes true: change in obsessive-compulsive disorder over the first months of the covid-19 pandemic
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590107/
https://www.ncbi.nlm.nih.gov/pubmed/34752943
http://dx.doi.org/10.1016/j.janxdis.2021.102493
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