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Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report

Ocular coloboma (OC) is a rare congenital anomaly and a product of a defect in embryogenesis. It is the result of fetal fissure closure error that ends with a persistent cleft. Colobomas are generally accompanied by visual loss. In this article, we present a case of bilateral iris, disc, and retina...

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Autores principales: Almasaud, Jluwi, Aledaili, Sara A, Alshammari, Reem S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590112/
https://www.ncbi.nlm.nih.gov/pubmed/34796081
http://dx.doi.org/10.7759/cureus.19521
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author Almasaud, Jluwi
Aledaili, Sara A
Alshammari, Reem S
author_facet Almasaud, Jluwi
Aledaili, Sara A
Alshammari, Reem S
author_sort Almasaud, Jluwi
collection PubMed
description Ocular coloboma (OC) is a rare congenital anomaly and a product of a defect in embryogenesis. It is the result of fetal fissure closure error that ends with a persistent cleft. Colobomas are generally accompanied by visual loss. In this article, we present a case of bilateral iris, disc, and retina coloboma that was managed with an anti-vascular endothelial growth factor (ranibizumab), and as a result, caused regression of the choroidal neovascular membranes and improved the patient's visual acuity. However, The patient will need lifelong follow-up to catch any retinochoroidal changes or development of cataract or glaucoma.
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spelling pubmed-85901122021-11-17 Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report Almasaud, Jluwi Aledaili, Sara A Alshammari, Reem S Cureus Ophthalmology Ocular coloboma (OC) is a rare congenital anomaly and a product of a defect in embryogenesis. It is the result of fetal fissure closure error that ends with a persistent cleft. Colobomas are generally accompanied by visual loss. In this article, we present a case of bilateral iris, disc, and retina coloboma that was managed with an anti-vascular endothelial growth factor (ranibizumab), and as a result, caused regression of the choroidal neovascular membranes and improved the patient's visual acuity. However, The patient will need lifelong follow-up to catch any retinochoroidal changes or development of cataract or glaucoma. Cureus 2021-11-13 /pmc/articles/PMC8590112/ /pubmed/34796081 http://dx.doi.org/10.7759/cureus.19521 Text en Copyright © 2021, Almasaud et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Ophthalmology
Almasaud, Jluwi
Aledaili, Sara A
Alshammari, Reem S
Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report
title Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report
title_full Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report
title_fullStr Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report
title_full_unstemmed Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report
title_short Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report
title_sort ocular coloboma with choroidal neovascular membrane: a case report
topic Ophthalmology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590112/
https://www.ncbi.nlm.nih.gov/pubmed/34796081
http://dx.doi.org/10.7759/cureus.19521
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