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Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report
Ocular coloboma (OC) is a rare congenital anomaly and a product of a defect in embryogenesis. It is the result of fetal fissure closure error that ends with a persistent cleft. Colobomas are generally accompanied by visual loss. In this article, we present a case of bilateral iris, disc, and retina...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590112/ https://www.ncbi.nlm.nih.gov/pubmed/34796081 http://dx.doi.org/10.7759/cureus.19521 |
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author | Almasaud, Jluwi Aledaili, Sara A Alshammari, Reem S |
author_facet | Almasaud, Jluwi Aledaili, Sara A Alshammari, Reem S |
author_sort | Almasaud, Jluwi |
collection | PubMed |
description | Ocular coloboma (OC) is a rare congenital anomaly and a product of a defect in embryogenesis. It is the result of fetal fissure closure error that ends with a persistent cleft. Colobomas are generally accompanied by visual loss. In this article, we present a case of bilateral iris, disc, and retina coloboma that was managed with an anti-vascular endothelial growth factor (ranibizumab), and as a result, caused regression of the choroidal neovascular membranes and improved the patient's visual acuity. However, The patient will need lifelong follow-up to catch any retinochoroidal changes or development of cataract or glaucoma. |
format | Online Article Text |
id | pubmed-8590112 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-85901122021-11-17 Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report Almasaud, Jluwi Aledaili, Sara A Alshammari, Reem S Cureus Ophthalmology Ocular coloboma (OC) is a rare congenital anomaly and a product of a defect in embryogenesis. It is the result of fetal fissure closure error that ends with a persistent cleft. Colobomas are generally accompanied by visual loss. In this article, we present a case of bilateral iris, disc, and retina coloboma that was managed with an anti-vascular endothelial growth factor (ranibizumab), and as a result, caused regression of the choroidal neovascular membranes and improved the patient's visual acuity. However, The patient will need lifelong follow-up to catch any retinochoroidal changes or development of cataract or glaucoma. Cureus 2021-11-13 /pmc/articles/PMC8590112/ /pubmed/34796081 http://dx.doi.org/10.7759/cureus.19521 Text en Copyright © 2021, Almasaud et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Ophthalmology Almasaud, Jluwi Aledaili, Sara A Alshammari, Reem S Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report |
title | Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report |
title_full | Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report |
title_fullStr | Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report |
title_full_unstemmed | Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report |
title_short | Ocular Coloboma With Choroidal Neovascular Membrane: A Case Report |
title_sort | ocular coloboma with choroidal neovascular membrane: a case report |
topic | Ophthalmology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590112/ https://www.ncbi.nlm.nih.gov/pubmed/34796081 http://dx.doi.org/10.7759/cureus.19521 |
work_keys_str_mv | AT almasaudjluwi ocularcolobomawithchoroidalneovascularmembraneacasereport AT aledailisaraa ocularcolobomawithchoroidalneovascularmembraneacasereport AT alshammarireems ocularcolobomawithchoroidalneovascularmembraneacasereport |