ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons

Nerve injury–induced changes of gene expression in dorsal root ganglion (DRG) are critical for neuropathic pain genesis. However, how these changes occur remains elusive. Here we report the down-regulation of zinc finger protein 382 (ZNF382) in injured DRG neurons after nerve injury. Rescuing this d...

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Detalles Bibliográficos
Autores principales: Ma, Longfei, Yu, Lina, Jiang, Bao-Chun, Wang, Jingkai, Guo, Xinying, Huang, Yangyuxin, Ren, Jinxuan, Sun, Na, Gao, Dave Schwinn, Ding, Hao, Lu, Jianan, Zhou, Hang, Zou, Lijing, Gao, Yibo, Wang, Lieju, Sun, Kai, Ming, Yue, Meng, Zhipeng, Tao, Yuan-Xiang, Yan, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590274/
https://www.ncbi.nlm.nih.gov/pubmed/34762123
http://dx.doi.org/10.1084/jem.20210920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590274/
https://www.ncbi.nlm.nih.gov/pubmed/34762123
http://dx.doi.org/10.1084/jem.20210920

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