Interleukin-10 improves stroke outcome by controlling the detrimental Interleukin-17A response

BACKGROUND: Lymphocytes have dichotomous functions in ischemic stroke. Regulatory T cells are protective, while IL-17A from innate lymphocytes promotes the infarct growth. With recent advances of T cell-subtype specific transgenic mouse models it now has become possible to study the complex interpla...

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Detalles Bibliográficos
Autores principales: Piepke, Marius, Clausen, Bettina H., Ludewig, Peter, Vienhues, Jonas H., Bedke, Tanja, Javidi, Ehsan, Rissiek, Björn, Jank, Larissa, Brockmann, Leonie, Sandrock, Inga, Degenhardt, Karoline, Jander, Alina, Roth, Vanessa, Schädlich, Ines S., Prinz, Immo, Flavell, Richard A., Kobayashi, Yasushi, Renné, Thomas, Gerloff, Christian, Huber, Samuel, Magnus, Tim, Gelderblom, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590298/
https://www.ncbi.nlm.nih.gov/pubmed/34772416
http://dx.doi.org/10.1186/s12974-021-02316-7

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