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Patients harboring uncommon EGFR exon 19 deletion-insertion mutations respond well to first-generation EGFR inhibitors and osimeritinib upon acquisition of T790M

BACKGROUND: In the existing next generation sequencing (NGS) system, epidermal growth factor receptor (EGFR) exon 19 deletion-insertion (19delins) is still interpreted into the category of EGFR exon 19 deletion (19del). However, the controversy exists whether the two mutation types have the similar...

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Detalles Bibliográficos
Autores principales:	Wang, Yurong, Zheng, Ruipan, Hu, Peizhu, Zhang, Ziheng, Shen, Shujing, Li, Xingya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590339/ https://www.ncbi.nlm.nih.gov/pubmed/34774017 http://dx.doi.org/10.1186/s12885-021-08942-x

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