Cargando…

Pleiotropy between language impairment and broader behavioral disorders—an investigation of both common and rare genetic variants

BACKGROUND: Language plays a major role in human behavior. For this reason, neurodevelopmental and psychiatric disorders in which linguistic ability is impaired could have a big impact on the individual’s social interaction and general wellbeing. Such disorders tend to have a strong genetic componen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nudel, Ron, Appadurai, Vivek, Buil, Alfonso, Nordentoft, Merete, Werge, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590378/ https://www.ncbi.nlm.nih.gov/pubmed/34773992 http://dx.doi.org/10.1186/s11689-021-09403-z

Ejemplares similares

Correction: Pleiotropy between language impairment and broader behavioral disorders—an investigation of both common and rare genetic variants
por: Nudel, Ron, et al.
Publicado: (2023)

O4.6. GENOME-WIDE ASSOCIATION STUDY, HERITABILITY ESTIMATION AND POLYGENIC RISK ANALYSIS OF SUSCEPTIBILITY TO INFECTIONS IN 65,534 INDIVIDUALS WITH SEVERE MENTAL DISORDERS AND POPULATION CONTROLS
por: Benros, Michael, et al.
Publicado: (2018)

A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness
por: Nudel, Ron, et al.
Publicado: (2020)

A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population
por: Nudel, Ron, et al.
Publicado: (2019)

Language deficits in specific language impairment, attention deficit/hyperactivity disorder, and autism spectrum disorder: An analysis of polygenic risk
por: Nudel, Ron, et al.
Publicado: (2019)

An investigation of NFXL1, a gene implicated in a study of specific language impairment
por: Nudel, Ron
Publicado: (2016)

Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks
por: Appadurai, Vivek, et al.
Publicado: (2023)

Maternal pregnancy-related infections and autism spectrum disorder—the genetic perspective
por: Nudel, Ron, et al.
Publicado: (2022)

Genome-Wide Studies of Specific Language Impairment
por: Reader, Rose H., et al.
Publicado: (2014)

Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate
por: Andreassen, Ole A., et al.
Publicado: (2013)

Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate
por: Andreassen, Ole A., et al.
Publicado: (2015)

Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity
por: Rajagopal, Veera M., et al.
Publicado: (2023)

Deep learning–based integration of genetics with registry data for stratification of schizophrenia and depression
por: Allesøe, Rosa Lundbye, et al.
Publicado: (2022)

Quantitative genome-wide association analyses of receptive language in the Danish High Risk and Resilience Study
por: Nudel, Ron, et al.
Publicado: (2020)

Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders
por: Nudel, Ron, et al.
Publicado: (2019)

Correction: Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorder
por: Nudel, Ron, et al.
Publicado: (2020)

Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes
por: Stepniak, Beata, et al.
Publicado: (2015)

Editorial: Establishing Genetic Pleiotropy to Identify Common Pharmacological Agents for Common Diseases
por: O’Mara, Tracy A., et al.
Publicado: (2019)

Antagonistic pleiotropy for carbon use is rare in new mutations
por: Sane, Mrudula, et al.
Publicado: (2018)

The Musical Abilities, Pleiotropy, Language, and Environment (MAPLE) Framework for Understanding Musicality-Language Links Across the Lifespan
por: Nayak, Srishti, et al.
Publicado: (2022)

Both rare and common genetic variants contribute to autism in the Faroe Islands
por: Leblond, Claire S, et al.
Publicado: (2019)

Genetic and epidemiological analyses of infection load and its relationship with psychiatric disorders
por: Nudel, Ron, et al.
Publicado: (2023)

T83. SUBSTANCE-INDUCED PSYCHOSIS LINKED TO BOTH INFECTIONS AND SCHIZOPHRENIA
por: Hjorthøj, Carsten, et al.
Publicado: (2020)

Improved detection of common variants in coronary artery disease and blood pressure using a pleiotropy cFDR method
por: Mao, Xiang-Jie, et al.
Publicado: (2019)

Associations of HLA alleles with specific language impairment
por: Nudel, Ron, et al.
Publicado: (2014)

Collapsing ROC approach for risk prediction research on both common and rare variants
por: Wei, Changshuai, et al.
Publicado: (2011)

Pleiotropy and synergistic cooperation
por: Queller, David C.
Publicado: (2019)

The Broader Opportunity Costs in the Broader Cost-Effectiveness Analysis Framework
por: Vallejo-Torres, Laura
Publicado: (2023)

Can Genetic Pleiotropy Replicate Common Clinical Constellations of Cardiovascular Disease and Risk?
por: Gottesman, Omri, et al.
Publicado: (2012)

Pleiotropy facilitates local adaptation to distant optima in common ragweed (Ambrosia artemisiifolia)
por: Hämälä, Tuomas, et al.
Publicado: (2020)

Extending the MR‐Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy
por: Rees, Jessica M. B., et al.
Publicado: (2017)

CAPE: An R Package for Combined Analysis of Pleiotropy and Epistasis
por: Tyler, Anna L., et al.
Publicado: (2013)

A unified framework for multi-locus association analysis of both common and rare variants
por: Shriner, Daniel, et al.
Publicado: (2011)

The genetic pleiotropy of musculoskeletal aging
por: Karasik, David, et al.
Publicado: (2012)

Pleiotropy among Common Genetic Loci Identified for Cardiometabolic Disorders and C-Reactive Protein
por: Ligthart, Symen, et al.
Publicado: (2015)

A Broader View
por: Goehl, Thomas J.
Publicado: (1996)

Broader horizons ahead
por: CERN Bulletin
Publicado: (2010)

Broad, broader, broadest
por: van Nunen, L.X., et al.
Publicado: (2015)

Broad, broader, broadest
por: van Nunen, L.X., et al.
Publicado: (2015)

Correction: Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_19asjatvmq407euu8dct7l3all