Cerebral Venous Sinus Thrombosis After BNT162b2 mRNA COVID-19 Vaccination

W present a rare case of cerebral venous sinus thrombosis after the BNT162b2 mRNA COVID-19 vaccine. A 61-year-old Japanese man developed a headache 10 days after the first dose of the vaccine. Magnetic resonance venography and contrast-enhanced brain MRI showed thrombosis in the superior sagittal si...

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Autores principales: Yamaguchi, Yoshitaka, Kimihira, Luna, Nagasawa, Hikaru, Seo, Kyoichi, Wada, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590453/
https://www.ncbi.nlm.nih.gov/pubmed/34796065
http://dx.doi.org/10.7759/cureus.18775
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author Yamaguchi, Yoshitaka
Kimihira, Luna
Nagasawa, Hikaru
Seo, Kyoichi
Wada, Manabu
author_facet Yamaguchi, Yoshitaka
Kimihira, Luna
Nagasawa, Hikaru
Seo, Kyoichi
Wada, Manabu
author_sort Yamaguchi, Yoshitaka
collection PubMed
description W present a rare case of cerebral venous sinus thrombosis after the BNT162b2 mRNA COVID-19 vaccine. A 61-year-old Japanese man developed a headache 10 days after the first dose of the vaccine. Magnetic resonance venography and contrast-enhanced brain MRI showed thrombosis in the superior sagittal sinus and the right transverse sinus. Anticoagulation with intravenous unfractionated heparin followed by oral warfarin was started. His headache improved, and brain MRI on day 22 showed resolution of thrombus. He was maintained on anticoagulation with warfarin and discharged without any neurological sequelae. This case is presented in the context of the relevant literature.
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spelling pubmed-85904532021-11-17 Cerebral Venous Sinus Thrombosis After BNT162b2 mRNA COVID-19 Vaccination Yamaguchi, Yoshitaka Kimihira, Luna Nagasawa, Hikaru Seo, Kyoichi Wada, Manabu Cureus Neurology W present a rare case of cerebral venous sinus thrombosis after the BNT162b2 mRNA COVID-19 vaccine. A 61-year-old Japanese man developed a headache 10 days after the first dose of the vaccine. Magnetic resonance venography and contrast-enhanced brain MRI showed thrombosis in the superior sagittal sinus and the right transverse sinus. Anticoagulation with intravenous unfractionated heparin followed by oral warfarin was started. His headache improved, and brain MRI on day 22 showed resolution of thrombus. He was maintained on anticoagulation with warfarin and discharged without any neurological sequelae. This case is presented in the context of the relevant literature. Cureus 2021-10-14 /pmc/articles/PMC8590453/ /pubmed/34796065 http://dx.doi.org/10.7759/cureus.18775 Text en Copyright © 2021, Yamaguchi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Yamaguchi, Yoshitaka
Kimihira, Luna
Nagasawa, Hikaru
Seo, Kyoichi
Wada, Manabu
Cerebral Venous Sinus Thrombosis After BNT162b2 mRNA COVID-19 Vaccination
title Cerebral Venous Sinus Thrombosis After BNT162b2 mRNA COVID-19 Vaccination
title_full Cerebral Venous Sinus Thrombosis After BNT162b2 mRNA COVID-19 Vaccination
title_fullStr Cerebral Venous Sinus Thrombosis After BNT162b2 mRNA COVID-19 Vaccination
title_full_unstemmed Cerebral Venous Sinus Thrombosis After BNT162b2 mRNA COVID-19 Vaccination
title_short Cerebral Venous Sinus Thrombosis After BNT162b2 mRNA COVID-19 Vaccination
title_sort cerebral venous sinus thrombosis after bnt162b2 mrna covid-19 vaccination
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590453/
https://www.ncbi.nlm.nih.gov/pubmed/34796065
http://dx.doi.org/10.7759/cureus.18775
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