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Nucleocapsid mutations R203K/G204R increase the infectivity, fitness, and virulence of SARS-CoV-2

Previous work found that the co-occurring mutations R203K/G204R on the SARS-CoV-2 nucleocapsid (N) protein are increasing in frequency among emerging variants of concern or interest. Through a combination of in silico analyses, this study demonstrates that R203K/G204R are adaptive, while large-scale...

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Detalles Bibliográficos
Autores principales:	Wu, Haibo, Xing, Na, Meng, Kaiwen, Fu, Beibei, Xue, Weiwei, Dong, Pan, Tang, Wanyan, Xiao, Yang, Liu, Gexin, Luo, Haitao, Zhu, Wenzhuang, Lin, Xiaoyuan, Meng, Geng, Zhu, Zhenglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Author(s). Published by Elsevier Inc. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590493/ https://www.ncbi.nlm.nih.gov/pubmed/34822776 http://dx.doi.org/10.1016/j.chom.2021.11.005

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