Cargando…

The effect of prehospital tranexamic acid on outcome in polytrauma patients with associated severe brain injury

INTRODUCTION: Tranexamic acid (TXA) has shown to be beneficial in selected patients with hemorrhagic shock. Recently, TXA has gained interest in isolated traumatic brain injury (TBI) patients with variable results. There are limited data on TXA in polytrauma with associated TBI. This study investiga...

Descripción completa

Detalles Bibliográficos
Autores principales:	van Wessem, Karlijn J. P., Jochems, Denise, Leenen, Luke P. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590807/ https://www.ncbi.nlm.nih.gov/pubmed/34775510 http://dx.doi.org/10.1007/s00068-021-01827-5

Ejemplares similares

Does Liberal Prehospital and In-Hospital Tranexamic Acid Influence Outcome in Severely Injured Patients? A Prospective Cohort Study
por: van Wessem, Karlijn J. P., et al.
Publicado: (2021)

Polytrauma patients with severe cervical spine injuries are different than with severe TBI despite similar AIS scores
por: van Wessem, Karlijn J. P., et al.
Publicado: (2022)

Geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone
por: van Wessem, Karlijn J. P., et al.
Publicado: (2020)

Incidence of acute respiratory distress syndrome and associated mortality in a polytrauma population
por: van Wessem, Karlijn J P, et al.
Publicado: (2018)

Dilemma of crystalloid resuscitation in non-exsanguinating polytrauma: what is too much?
por: van Wessem, Karlijn, et al.
Publicado: (2020)

Is chest imaging relevant in diagnosing acute respiratory distress syndrome in polytrauma patients? A population-based cohort study
por: van Wessem, Karlijn Julia Patricia, et al.
Publicado: (2019)

Incidence, causes and consequences of moderate and severe traumatic brain injury as determined by Abbreviated Injury Score in the Netherlands
por: Jochems, Denise, et al.
Publicado: (2021)

Global changes in mortality rates in polytrauma patients admitted to the ICU—a systematic review
por: van Breugel, Johanna M. M., et al.
Publicado: (2020)

Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS) after Polytrauma: A Rare Syndrome with Major Consequences
por: Hesselink, Lillian, et al.
Publicado: (2020)

Physiology dictated treatment after severe trauma: timing is everything
por: van Wessem, Karlijn J. P., et al.
Publicado: (2022)

Outcome in Patients with Isolated Moderate to Severe Traumatic Brain Injury
por: Jochems, D., et al.
Publicado: (2018)

Letter to the editor regarding Latent class analysis to predict intensive care outcomes in Acute Respiratory Distress Syndrome: a proposal of two pulmonary phenotypes
por: van Wessem, Karlijn J. P., et al.
Publicado: (2021)

Attenuation of MODS-related and ARDS-related mortality makes infectious complications a remaining challenge in the severely injured
por: van Wessem, Karlijn J.P., et al.
Publicado: (2020)

Prehospital tranexamic acid for trauma victims
por: Omori, Kazuhiko, et al.
Publicado: (2023)

Effect of tranexamic acid administration on acute traumatic coagulopathy in rats with polytrauma and hemorrhage
por: Wu, Xiaowu, et al.
Publicado: (2019)

Prehospital administration of tranexamic acid in trauma patients
por: Wafaisade, Arasch, et al.
Publicado: (2016)

Prehospital tranexamic acid: what is the current evidence?
por: Napolitano, Lena M
Publicado: (2017)

Current treatment and outcomes of traumatic sternovertebral fractures: a systematic review
por: Klei, Dorine S., et al.
Publicado: (2020)

No Need for Sternal Fixation in Traumatic Sternovertebral Fractures: Outcomes of a 10-Year Retrospective Cohort Study
por: Klei, Dorine S., et al.
Publicado: (2020)

Prehospital time and mortality in polytrauma patients: a retrospective analysis
por: Berkeveld, E., et al.
Publicado: (2021)

The association of patient and trauma characteristics with the health-related quality of life in a Dutch trauma population
por: Gunning, Amy, et al.
Publicado: (2017)

Mortality Risk Factors of Severely Injured Polytrauma Patients (Prehospital Mortality Prediction Score)
por: Vorbeck, Jana, et al.
Publicado: (2023)

Inter-rater reliability of the Abbreviated Injury Scale scores in patients with severe head injury shows good inter-rater agreement but variability between countries. An inter-country comparison study
por: Gunning, Amy C., et al.
Publicado: (2022)

Current treatment and outcomes of traumatic sternal fractures—a systematic review
por: Klei, Dorine S., et al.
Publicado: (2018)

Neutrophil heterogeneity and its role in infectious complications after severe trauma
por: Hesselink, Lillian, et al.
Publicado: (2019)

Prehospital Use of the Intubating Laryngeal Mask Airway in Patients with Severe Polytrauma: A Case Series
por: Mason, Andrew M.
Publicado: (2009)

Impact of severe polytrauma on severe brain injured patients
por: Sartzi, M, et al.
Publicado: (2006)

Efficacy and Safety of Tranexamic Acid in Prehospital Traumatic Hemorrhagic Shock: Outcomes of the Cal-PAT Study
por: Neeki, Michael M., et al.
Publicado: (2017)

Polytrauma: update on basic science and clinical evidence
por: Nauth, Aaron, et al.
Publicado: (2021)

Distribution and treatment of clavicular fractures in monotrauma and polytrauma patients
por: Ferree, Steven, et al.
Publicado: (2014)

Underlying disease determines the risk of an open abdomen treatment, final closure, however, is determined by the surgical abdominal history
por: Karhof, Steffi, et al.
Publicado: (2019)

Tranexamic Acid in Civilian Trauma Care in the California Prehospital Antifibrinolytic Therapy Study
por: Neeki, Michael M., et al.
Publicado: (2018)

Incidence and Nature of Lower-Limb Deep Vein Thrombosis in Patients with Polytrauma on Thromboprophylaxis: A Prospective Cohort Study
por: Chowdhury, Sharfuddin, et al.
Publicado: (2021)

An increase in myeloid cells after severe injury is associated with normal fracture healing: a retrospective study of 62 patients with a femoral fracture
por: Hesselink, Lillian, et al.
Publicado: (2018)

Polytrauma and Multiple Severity Scores
por: CERNEA, DANIELA, et al.
Publicado: (2014)

Visualization of the inflammatory response to injury by neutrophil phenotype categories: Neutrophil phenotypes after trauma
por: de Fraiture, Emma J., et al.
Publicado: (2022)

Protocol for a multicentre prehospital randomised controlled trial investigating tranexamic acid in severe trauma: the PATCH-Trauma trial
por: Mitra, Biswadev, et al.
Publicado: (2021)

Efficacy of tranexamic acid in patients with traumatic brain injury
por: Kawada, Tomoyuki
Publicado: (2020)

Demographic Patterns and Outcomes of Patients in Level I Trauma Centers in Three International Trauma Systems
por: Gunning, Amy C., et al.
Publicado: (2015)

Timing of repair and mesh use in traumatic abdominal wall defects: a systematic review and meta-analysis of current literature
por: Karhof, Steffi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_h7m4mk03pfc39pkrdj0nr5rln2