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A Case Report of Extensive Pyoderma Gangrenosum on the Upper Third of the Body
Pyoderma gangrenosum (PG) is a sterile inflammatory neutrophilic dermatosis that can present as a peristomal, pustular, bullous, vegetative, or ulcerative variant. It commonly affects the lower extremities, mainly in the pretibial area. We describe a case of extensive PG in an 18-year-old Indonesian...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590941/ https://www.ncbi.nlm.nih.gov/pubmed/34785923 http://dx.doi.org/10.2147/CCID.S337508 |
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author | Gunawan, Hendra Maharani, Retno Hesty Achdiat, Pati Aji Hindritiani, Reti |
author_facet | Gunawan, Hendra Maharani, Retno Hesty Achdiat, Pati Aji Hindritiani, Reti |
author_sort | Gunawan, Hendra |
collection | PubMed |
description | Pyoderma gangrenosum (PG) is a sterile inflammatory neutrophilic dermatosis that can present as a peristomal, pustular, bullous, vegetative, or ulcerative variant. It commonly affects the lower extremities, mainly in the pretibial area. We describe a case of extensive PG in an 18-year-old Indonesian man, involving the upper third of the body. Dermatological examination showed multiple painful ulcers with violaceous borders on the face, occipital region of scalp, neck, shoulder, upper chest, and back. The diagnosis of PG was established based on the histopathological examination that revealed massive dermal neutrophilic infiltration mixed with lymphocytic inflammatory infiltrates accompanied by leukocytoclastic vasculitis. The patient was treated with methylprednisolone equivalent to 1 mg/kg/day of prednisone. An excellent response to therapy also confirmed the diagnosis of PG. Since lesions of PG can appear on any part of the body, including the upper third of the body, a complete and appropriate examination is useful in establishing diagnosis. |
format | Online Article Text |
id | pubmed-8590941 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-85909412021-11-15 A Case Report of Extensive Pyoderma Gangrenosum on the Upper Third of the Body Gunawan, Hendra Maharani, Retno Hesty Achdiat, Pati Aji Hindritiani, Reti Clin Cosmet Investig Dermatol Case Report Pyoderma gangrenosum (PG) is a sterile inflammatory neutrophilic dermatosis that can present as a peristomal, pustular, bullous, vegetative, or ulcerative variant. It commonly affects the lower extremities, mainly in the pretibial area. We describe a case of extensive PG in an 18-year-old Indonesian man, involving the upper third of the body. Dermatological examination showed multiple painful ulcers with violaceous borders on the face, occipital region of scalp, neck, shoulder, upper chest, and back. The diagnosis of PG was established based on the histopathological examination that revealed massive dermal neutrophilic infiltration mixed with lymphocytic inflammatory infiltrates accompanied by leukocytoclastic vasculitis. The patient was treated with methylprednisolone equivalent to 1 mg/kg/day of prednisone. An excellent response to therapy also confirmed the diagnosis of PG. Since lesions of PG can appear on any part of the body, including the upper third of the body, a complete and appropriate examination is useful in establishing diagnosis. Dove 2021-11-10 /pmc/articles/PMC8590941/ /pubmed/34785923 http://dx.doi.org/10.2147/CCID.S337508 Text en © 2021 Gunawan et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Case Report Gunawan, Hendra Maharani, Retno Hesty Achdiat, Pati Aji Hindritiani, Reti A Case Report of Extensive Pyoderma Gangrenosum on the Upper Third of the Body |
title | A Case Report of Extensive Pyoderma Gangrenosum on the Upper Third of the Body |
title_full | A Case Report of Extensive Pyoderma Gangrenosum on the Upper Third of the Body |
title_fullStr | A Case Report of Extensive Pyoderma Gangrenosum on the Upper Third of the Body |
title_full_unstemmed | A Case Report of Extensive Pyoderma Gangrenosum on the Upper Third of the Body |
title_short | A Case Report of Extensive Pyoderma Gangrenosum on the Upper Third of the Body |
title_sort | case report of extensive pyoderma gangrenosum on the upper third of the body |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590941/ https://www.ncbi.nlm.nih.gov/pubmed/34785923 http://dx.doi.org/10.2147/CCID.S337508 |
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