A case with SARS-CoV-2 reinfection from India

A healthcare worker presented with fever, cough, headache and tested positive by SARS-CoV-2 real time reverse transcriptase polymerase chain reaction (qRT-PCR). He got admitted to hospital and recovered after 14 days. After 2 months, as a screening protocol considering the high risk setup he got tes...

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Autores principales: Munivenkatappa, Ashok, Sahay, Rima R., Deshpande, Gururaj R., Patil, Deepak Y., Shete, Anita M., Sapkal, Gajanan N., Kumar, Ravish, Narayana, Marappa, Yadav, Pragya D., Shettar, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Association of Medical Microbiologists. Published by Elsevier B.V. 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590946/
https://www.ncbi.nlm.nih.gov/pubmed/34789389
http://dx.doi.org/10.1016/j.ijmmb.2021.09.010
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author Munivenkatappa, Ashok
Sahay, Rima R.
Deshpande, Gururaj R.
Patil, Deepak Y.
Shete, Anita M.
Sapkal, Gajanan N.
Kumar, Ravish
Narayana, Marappa
Yadav, Pragya D.
Shettar, Vijay
author_facet Munivenkatappa, Ashok
Sahay, Rima R.
Deshpande, Gururaj R.
Patil, Deepak Y.
Shete, Anita M.
Sapkal, Gajanan N.
Kumar, Ravish
Narayana, Marappa
Yadav, Pragya D.
Shettar, Vijay
author_sort Munivenkatappa, Ashok
collection PubMed
description A healthcare worker presented with fever, cough, headache and tested positive by SARS-CoV-2 real time reverse transcriptase polymerase chain reaction (qRT-PCR). He got admitted to hospital and recovered after 14 days. After 2 months, as a screening protocol considering the high risk setup he got tested and again found to be positive for SARS-CoV-2 by qRT-PCR. Our patient had detectable levels of Anti-SARS-CoV-2 IgG antibodies during the reinfection but found negative for Neutralizing antibodies (NAb). Our findings suggest that the person after the initial infection might not develop the desired protective immunity to prevent the reinfection as demonstrated by absence of NAb.
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spelling pubmed-85909462021-11-15 A case with SARS-CoV-2 reinfection from India Munivenkatappa, Ashok Sahay, Rima R. Deshpande, Gururaj R. Patil, Deepak Y. Shete, Anita M. Sapkal, Gajanan N. Kumar, Ravish Narayana, Marappa Yadav, Pragya D. Shettar, Vijay Indian J Med Microbiol Case Report A healthcare worker presented with fever, cough, headache and tested positive by SARS-CoV-2 real time reverse transcriptase polymerase chain reaction (qRT-PCR). He got admitted to hospital and recovered after 14 days. After 2 months, as a screening protocol considering the high risk setup he got tested and again found to be positive for SARS-CoV-2 by qRT-PCR. Our patient had detectable levels of Anti-SARS-CoV-2 IgG antibodies during the reinfection but found negative for Neutralizing antibodies (NAb). Our findings suggest that the person after the initial infection might not develop the desired protective immunity to prevent the reinfection as demonstrated by absence of NAb. Indian Association of Medical Microbiologists. Published by Elsevier B.V. 2022 2021-11-15 /pmc/articles/PMC8590946/ /pubmed/34789389 http://dx.doi.org/10.1016/j.ijmmb.2021.09.010 Text en © 2021 Indian Association of Medical Microbiologists. Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Munivenkatappa, Ashok
Sahay, Rima R.
Deshpande, Gururaj R.
Patil, Deepak Y.
Shete, Anita M.
Sapkal, Gajanan N.
Kumar, Ravish
Narayana, Marappa
Yadav, Pragya D.
Shettar, Vijay
A case with SARS-CoV-2 reinfection from India
title A case with SARS-CoV-2 reinfection from India
title_full A case with SARS-CoV-2 reinfection from India
title_fullStr A case with SARS-CoV-2 reinfection from India
title_full_unstemmed A case with SARS-CoV-2 reinfection from India
title_short A case with SARS-CoV-2 reinfection from India
title_sort case with sars-cov-2 reinfection from india
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590946/
https://www.ncbi.nlm.nih.gov/pubmed/34789389
http://dx.doi.org/10.1016/j.ijmmb.2021.09.010
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