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Metabolomics and Whole-Exome Sequencing in Patients with Differential Sensitivity to Sevoflurane: A Protocol for a Prospective Observational Trial

Introduction: Different sensitivity to volatile anesthetics in Drosophila, nematodes and mice is related to mutation of energy metabolism genes. In clinical practice, we find that the end-tidal sevoflurane concentration (ET(sevo)) differs among patients at the same depth of anesthesia, indicating th...

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Detalles Bibliográficos
Autores principales:	Wei, Yiyong, Zhang, Donghang, Zuo, Yunxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591073/ https://www.ncbi.nlm.nih.gov/pubmed/34790114 http://dx.doi.org/10.3389/fphar.2021.621159

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