Beta-Lapachone Attenuates BMSC-Mediated Neuroblastoma Malignant Transformation by Inhibiting Gal-3/Gal-3BP/IL6 Axis

The inflammatory factor IL6 secreted by bone marrow mesenchymal stem cells (BMSCs) in the tumor microenvironment (TME) facilitates the survival and therapeutic resistance of neuroblastoma (NB). Here, we found that IL6 expression in primary tumor tissues or bone marrow (BM) metastases was closely ass...

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Detalles Bibliográficos
Autores principales: Zhou, Yang, Yan, Hui, Zhou, Qiang, Feng, Ruiling, Wang, Penggao, Yang, Fang, Zhang, Yaodong, Yuan, Ziqiao, Zhai, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591123/
https://www.ncbi.nlm.nih.gov/pubmed/34790130
http://dx.doi.org/10.3389/fphar.2021.766909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591123/
https://www.ncbi.nlm.nih.gov/pubmed/34790130
http://dx.doi.org/10.3389/fphar.2021.766909

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