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Restoring HOXD10 Exhibits Therapeutic Potential for Ameliorating Malignant Progression and 5-Fluorouracil Resistance in Colorectal Cancer

Emerging evidence suggests that hypermethylation of HOXD10 plays an important role in human cancers. However, the biological and clinical impacts of HOXD10 overmethylation and its downstream targets in colorectal cancer remain unknown. We evaluated the methylation level of HOXD10 in paired cancer an...

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Detalles Bibliográficos
Autores principales: Pan, Weijie, Wang, Kaijing, Li, Jiayong, Li, Hanhua, Cai, Yuchan, Zhang, Min, Wang, Aili, Wu, Yazhou, Gao, Wei, Weng, Wenhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591167/
https://www.ncbi.nlm.nih.gov/pubmed/34790580
http://dx.doi.org/10.3389/fonc.2021.771528