Cargando…

The Multifaceted Roles of B Cells in the Thymus: From Immune Tolerance to Autoimmunity

The thymus is home to a significant number of resident B cells which possess several unique characteristics regarding their origin, phenotype and function. Evidence shows that they originate both from precursors that mature intrathymically and as the entry of recirculating mature B cells. Under stea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Castañeda, Justine, Hidalgo, Yessia, Sauma, Daniela, Rosemblatt, Mario, Bono, María Rosa, Núñez, Sarah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591215/ https://www.ncbi.nlm.nih.gov/pubmed/34790201 http://dx.doi.org/10.3389/fimmu.2021.766698

Ejemplares similares

Alloreactive Regulatory T Cells Allow the Generation of Mixed Chimerism and Transplant Tolerance
por: Ruiz, Paulina, et al.
Publicado: (2015)

Adoptive transfer of autoimmune splenic dendritic cells to lupus-prone mice triggers a B lymphocyte humoral response
por: Sauma, Daniela, et al.
Publicado: (2017)

Transplant Tolerance: New Insights and Strategies for Long-Term Allograft Acceptance
por: Ruiz, Paulina, et al.
Publicado: (2013)

Thymic B Cells Promote Germinal Center-Like Structures and the Expansion of Follicular Helper T Cells in Lupus-Prone Mice
por: Hidalgo, Yessia, et al.
Publicado: (2020)

In Vitro-Generated Tc17 Cells Present a Memory Phenotype and Serve As a Reservoir of Tc1 Cells In Vivo
por: Flores-Santibáñez, Felipe, et al.
Publicado: (2018)

Retinoic Acid as a Modulator of T Cell Immunity
por: Bono, Maria Rosa, et al.
Publicado: (2016)

Vitamin A Impairs the Reprogramming of Tregs into IL-17-Producing Cells during Intestinal Inflammation
por: Tejón, Gabriela, et al.
Publicado: (2015)

Purinergic Signaling as a Regulator of Th17 Cell Plasticity
por: Fernández, Dominique, et al.
Publicado: (2016)

Understanding the Multifaceted Role of Neutrophils in Cancer and Autoimmune Diseases
por: Wang, Xu, et al.
Publicado: (2018)

Phenotypic and functional alterations of peritoneal macrophages in lupus-prone mice
por: Tejon, Gabriela, et al.
Publicado: (2022)

The Contribution of Chemokines and Migration to the Induction of Central Tolerance in the Thymus
por: Hu, Zicheng, et al.
Publicado: (2015)

P2X7 Receptor at the Crossroads of T Cell Fate
por: Rivas-Yáñez, Elizabeth, et al.
Publicado: (2020)

Origin, phenotype and autoimmune potential of T cells in human immune system mice receiving neonatal human thymus tissue
por: Talaie, Tara, et al.
Publicado: (2023)

miR-146a in Myasthenia Gravis Thymus Bridges Innate Immunity With Autoimmunity and Is Linked to Therapeutic Effects of Corticosteroids
por: Bortone, Federica, et al.
Publicado: (2020)

The role of thymus- and extrathymus-derived regulatory T cells in maternal-fetal tolerance
por: Li, Zhengjuan, et al.
Publicado: (2023)

The Repertoires of Peptides Presented by MHC-II in the Thymus and in Peripheral Tissue: A Clue for Autoimmunity?
por: Collado, Javier A., et al.
Publicado: (2013)

Genetic basis of defects in immune tolerance underlying the development of autoimmunity
por: Hocking, Anne M., et al.
Publicado: (2022)

Thymus and autoimmunity
por: Marx, Alexander, et al.
Publicado: (2021)

Ecto-5′-Nucleotidase (CD73) Regulates the Survival of CD8+ T Cells
por: Rosemblatt, Mariana V., et al.
Publicado: (2021)

Toll-Like Receptor Activation in Immunity vs. Tolerance in Autoimmune Diabetes
por: Gülden, Elke, et al.
Publicado: (2014)

CD73 Ectonucleotidase Restrains CD8+ T Cell Metabolic Fitness and Anti-tumoral Activity
por: Briceño, Pedro, et al.
Publicado: (2021)

Multifaceted Role of Neuropilins in the Immune System: Potential Targets for Immunotherapy
por: Roy, Sohini, et al.
Publicado: (2017)

Revisiting Thymus Function
por: Miller, Jacques F. A. P.
Publicado: (2014)

The Role of Proteasomes in the Thymus
por: Frantzeskakis, Melina, et al.
Publicado: (2021)

Thymus Degeneration and Regeneration
por: Duah, Maxwell, et al.
Publicado: (2021)

Regulatory B Cells in Pregnancy: Lessons from Autoimmunity, Graft Tolerance, and Cancer
por: Guzman-Genuino, Ruth Marian, et al.
Publicado: (2017)

NLRX1 Is a Multifaceted and Enigmatic Regulator of Immune System Function
por: Nagai-Singer, Margaret A., et al.
Publicado: (2019)

Editorial: Harnessing the Participation of Dendritic Cells in Immunity and Tolerance
por: Boscardin, Silvia Beatriz, et al.
Publicado: (2020)

It Takes a Village: The Multifaceted Immune Response to Mycobacterium tuberculosis Infection and Vaccine-Induced Immunity
por: Larsen, Sasha E., et al.
Publicado: (2022)

Convergences and Divergences of Thymus- and Peripherally Derived Regulatory T Cells in Cancer
por: Burocchi, Alessia, et al.
Publicado: (2013)

On Discovering Thymus–Marrow Synergism
por: Claman, Henry N.
Publicado: (2014)

Transgenic Exosomes for Thymus Regeneration
por: Banfai, Krisztina, et al.
Publicado: (2019)

TRAF3 as a Multifaceted Regulator of B Lymphocyte Survival and Activation
por: Bishop, Gail A., et al.
Publicado: (2018)

Paraneoplastic Autoimmunity in Thymus Tumors
por: Marx, Alexander, et al.
Publicado: (1998)

Clinical Spectrum of SCID: The Key is in the Thymus?
por: van der Burg, Mirjam, et al.
Publicado: (2014)

Regulatory T-Cell Development in the Human Thymus
por: Caramalho, Íris, et al.
Publicado: (2015)

Exosomes in the Thymus: Antigen Transfer and Vesicles
por: Skogberg, Gabriel, et al.
Publicado: (2015)

Postnatal Involution and Counter-Involution of the Thymus
por: Cowan, Jennifer E., et al.
Publicado: (2020)

Editorial: Revisiting the thymus: the origin of T cells
por: Lin, Xiaoxi, et al.
Publicado: (2023)

Age-Related Changes on CD40 Promotor Methylation and Immune Gene Expressions in Thymus of Chicken
por: Li, Yulong, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_bvv93vcljqm9bkoii1598qdg3t