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Case Report: Interferon- γ Rescues Monocytic Human Leukocyte Antigen Receptor (mHLA-DR) Function in a COVID-19 Patient With ARDS and Superinfection With Multiple MDR 4MRGN Bacterial Strains
BACKGROUND: CD14+ monocytes present antigens to adaptive immune cells via monocytic human leukocyte antigen receptor (mHLA-DR), which is described as an immunological synapse. Reduced levels of mHLA-DR can display an acquired immune defect, which is often found in sepsis and predisposes for secondar...
Autores principales: | Grimm, Clemens, Dickel, Steffen, Grundmann, Julian, Payen, Didier, Schanz, Julie, Zautner, Andreas Erich, Tampe, Björn, Moerer, Onnen, Winkler, Martin Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591280/ https://www.ncbi.nlm.nih.gov/pubmed/34790197 http://dx.doi.org/10.3389/fimmu.2021.753849 |
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