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Mitophagy Protects the Retina Against Anti-Vascular Endothelial Growth Factor Therapy-Driven Hypoxia via Hypoxia-Inducible Factor-1α Signaling

Anti-VEGF drugs are first-line treatments for retinal neovascular diseases, but these anti-angiogenic agents may also aggravate retinal damage by inducing hypoxia. Mitophagy can protect against hypoxia by maintaining mitochondrial quality, thereby sustaining metabolic homeostasis and reducing reacti...

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Detalles Bibliográficos
Autores principales:	Sun, Yimeng, Wen, Feng, Yan, Chun, Su, Lishi, Luo, Jiawen, Chi, Wei, Zhang, Shaochong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591297/ https://www.ncbi.nlm.nih.gov/pubmed/34790659 http://dx.doi.org/10.3389/fcell.2021.727822

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