Cargando…

A tumor-penetrable drug nanococktail made from human histones for interventional nucleus-targeted chemophotothermal therapy of drug-resistant tumors

Nanoparticle-based chemophotothermal therapy (CPT) is a promising treatment for multidrug resistant tumors. In this study, a drug nanococktail of DIR825@histone was developed by employing doxorubicin (DOX), NIR dye IR825 and human histones for interventional nucleus-targeted CPT of multidrug resista...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Jianquan, Tan, Dongsheng, Lou, Chenmei, Guo, Shiying, Jin, Xing, Qu, Haijing, Jing, Lijia, Li, Sijin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	KeAi Publishing 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591402/ https://www.ncbi.nlm.nih.gov/pubmed/34820588 http://dx.doi.org/10.1016/j.bioactmat.2021.07.018

Ejemplares similares

Platelet-camouflaged nanococktail: Simultaneous inhibition of drug-resistant tumor growth and metastasis via a cancer cells and tumor vasculature dual-targeting strategy
por: Jing, Lijia, et al.
Publicado: (2018)

Combinatorial nanococktails via self-assembling lipid prodrugs for synergistically overcoming drug resistance and effective cancer therapy
por: Li, Tongyu, et al.
Publicado: (2022)

Fabrication of doxorubicin-gated mesoporous polydopamine nanoplatforms for multimode imaging-guided synergistic chemophotothermal therapy of tumors
por: Yang, Min, et al.
Publicado: (2020)

Chemodrug-gated mesoporous nanoplatform for new near-infrared light controlled drug release and synergistic chemophotothermal therapy of tumours
por: Fu, Cuiping, et al.
Publicado: (2022)

Nanococktail Based on AIEgens and Semiconducting Polymers: A Single Laser Excited Image-Guided Dual Photothermal Therapy
por: Long, Zi, et al.
Publicado: (2020)

Reactive Oxygen Species-Responsive Nanococktail With Self-Amplificated Drug Release for Efficient Co-Delivery of Paclitaxel/Cucurbitacin B and Synergistic Treatment of Gastric Cancer
por: Pang, Lijun, et al.
Publicado: (2022)

GE11 Peptide Conjugated Liposomes for EGFR-Targeted and Chemophotothermal Combined Anticancer Therapy
por: Huang, Xueqin, et al.
Publicado: (2021)

A Tumor-Specific Tissue-Penetrating Peptide Enhances the Efficacy of Chemotherapy Drugs in Gastric Cancer
por: Jin, Zhian, et al.
Publicado: (2018)

Ultrasonic Enhancement of Drug Penetration in Solid Tumors
por: Lai, Chun-Yen, et al.
Publicado: (2013)

Strategies to Increase Drug Penetration in Solid Tumors
por: Choi, Il-Kyu, et al.
Publicado: (2013)

Editorial: Enhancing Drug Delivery and Tumor Penetration
por: Tang, Yuxia, et al.
Publicado: (2021)

Gold Nanocage-Incorporated Poly(ε-Caprolactone) (PCL) Fibers for Chemophotothermal Synergistic Cancer Therapy
por: Park, Ju Hyang, et al.
Publicado: (2019)

Leukocyte Membrane-Coated Liquid Metal Nanoswimmers for Actively Targeted Delivery and Synergistic Chemophotothermal Therapy
por: Wang, Daolin, et al.
Publicado: (2020)

Recent advances in drug delivery systems for enhancing drug penetration into tumors
por: He, Bin, et al.
Publicado: (2020)

Improving Drug Uptake and Penetration into Tumors: Current and Forthcoming Opportunities
por: Marcucci, Fabrizio, et al.
Publicado: (2013)

Mathematical Based Calculation of Drug Penetration Depth in Solid Tumors
por: Namazi, Hamidreza, et al.
Publicado: (2016)

Nanomedicine Strategies to Enhance Tumor Drug Penetration in Pancreatic Cancer
por: Lu, Tao, et al.
Publicado: (2021)

iRGD Peptide as a Tumor-Penetrating Enhancer for Tumor-Targeted Drug Delivery
por: Kang, Sujin, et al.
Publicado: (2020)

Tumor-Microenvironment- Responsive Size-Shrinkable Drug-Delivery Nanosystems for Deepened Penetration Into Tumors
por: Cheng, Xiaoliang, et al.
Publicado: (2020)

Sequentially Triggered Nanoparticles with Tumor Penetration and Intelligent Drug Release for Pancreatic Cancer Therapy
por: He, Xi, et al.
Publicado: (2018)

Carbon Nanodots for On Demand Chemophotothermal Therapy Combination to Elicit Necroptosis: Overcoming Apoptosis Resistance in Breast Cancer Cell Lines
por: Nicosia, Aldo, et al.
Publicado: (2020)

Morphophenotypic classification of tumor organoids as an indicator of drug exposure and penetration potential
por: Karolak, Aleksandra, et al.
Publicado: (2019)

Nanocarrier-Mediated Targeting of Tumor and Tumor Vascular Cells Improves Uptake and Penetration of Drugs into Neuroblastoma
por: Pastorino, Fabio, et al.
Publicado: (2013)

Histone demethylase KDM5A promotes tumorigenesis of osteosarcoma tumor
por: Peng, Daohu, et al.
Publicado: (2021)

Doxorubicin-Loaded MnO(2)@Zeolitic Imidazolate Framework-8 Nanoparticles as a Chemophotothermal System for Lung Cancer Therapy
por: Tan, Cheng, et al.
Publicado: (2021)

Tumor-targeting delivery of herb-based drugs with cell-penetrating/tumor-targeting peptide-modified nanocarriers
por: Kebebe, Dereje, et al.
Publicado: (2018)

Current Advances in Mathematical Modeling of Anti-Cancer Drug Penetration into Tumor Tissues
por: Kim, MunJu, et al.
Publicado: (2013)

A Mechanistic Tumor Penetration Model to Guide Antibody Drug Conjugate Design
por: Vasalou, Christina, et al.
Publicado: (2015)

Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors
por: Bartelink, Imke H., et al.
Publicado: (2017)

Design of new acid-activated cell-penetrating peptides for tumor drug delivery
por: Yao, Jia, et al.
Publicado: (2017)

Tumor Activated Cell Penetrating Peptides to Selectively Deliver Immune Modulatory Drugs
por: Hingorani, Dina V., et al.
Publicado: (2021)

TIMP‐1‐expressing breast tumor spheroids for the evaluation of drug penetration and efficacy
por: Bae, In Yeong, et al.
Publicado: (2021)

Uncovering the Fate and Risks of Intravenously Injected Prussian Blue Nanoparticles in mice by an Integrated Methodology of Toxicology, Pharmacokinetics, Proteomics, and Metabolomics
por: Qu, Haijing, et al.
Publicado: (2023)

Registered report: Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs
por: Kandela, Irawati, et al.
Publicado: (2015)

Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors
por: Torok, Szilvia, et al.
Publicado: (2017)

Replication Study: Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs
por: Mantis, Christine, et al.
Publicado: (2017)

Tumor Drug Penetration Measurements Could Be the Neglected Piece of the Personalized Cancer Treatment Puzzle
por: Bartelink, Imke H., et al.
Publicado: (2018)

Apoptotic body–mediated intercellular delivery for enhanced drug penetration and whole tumor destruction
por: Zhao, Dongyang, et al.
Publicado: (2021)

Size and charge dual-transformable mesoporous nanoassemblies for enhanced drug delivery and tumor penetration
por: Chen, Liang, et al.
Publicado: (2020)

Enhancing drug penetration in solid tumors via nanomedicine: Evaluation models, strategies and perspectives
por: Shen, Xiaoding, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3u0jrn4v4d1njlbrbhaf42r70t