The long non-coding RNA CDK6-AS1 overexpression impacts on acute myeloid leukemia differentiation and mitochondrial dynamics

Patients with acute myeloid leukemia (AML) carrying high-risk genetic lesions or high residual disease levels after therapy are particularly exposed to the risk of relapse. Here, we identified the long non-coding RNA CDK6-AS1 able to cluster an AML subgroup with peculiar gene signatures linked to he...

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Detalles Bibliográficos
Autores principales: Porcù, Elena, Benetton, Maddalena, Bisio, Valeria, Da Ros, Ambra, Tregnago, Claudia, Borella, Giulia, Zanon, Carlo, Bordi, Matteo, Germano, Giuseppe, Manni, Sabrina, Campello, Silvia, Rao, Dinesh S., Locatelli, Franco, Pigazzi, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591413/
https://www.ncbi.nlm.nih.gov/pubmed/34816103
http://dx.doi.org/10.1016/j.isci.2021.103350

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