Resolving macrophage polarization through distinct Ca(2+) entry channel that maintains intracellular signaling and mitochondrial bioenergetics

Transformation of naive macrophages into classically (M1) or alternatively (M2) activated macrophages regulates the inflammatory response. Here, we identified that distinct Ca(2+) entry channels determine the IFNγ-induced M1 or IL-4-induced M2 transition. Naive or M2 macrophages exhibit a robust Ca(...

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Detalles Bibliográficos
Autores principales: Nascimento Da Conceicao, Viviane, Sun, Yuyang, Ramachandran, Karthik, Chauhan, Arun, Raveendran, Amritha, Venkatesan, Manigandan, DeKumar, Bony, Maity, Soumya, Vishnu, Neelanjan, Kotsakis, George A., Worley, Paul F., Gill, Donald L., Mishra, Bibhuti B., Madesh, Muniswamy, Singh, Brij B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591423/
https://www.ncbi.nlm.nih.gov/pubmed/34816101
http://dx.doi.org/10.1016/j.isci.2021.103339

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