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A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center

Mucormycosis is an opportunistic fungal infection. India faced an unprecedented increase in patients with post coronavirus disease 2019 (COVID-19) associated rhino-orbito-cerebral mucormycosis (ROCM). This study proposes a grading system which correlates the extent of the disease with the management...

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Autores principales: Vaid, Neelam, Mishra, Prasun, Gokhale, Nikhil, Vaid, Sanjay, Vaze, Varada, Kothadiya, Ajay, Deka, Trisha, Agarwal, Rashmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591427/
https://www.ncbi.nlm.nih.gov/pubmed/34804905
http://dx.doi.org/10.1007/s12070-021-02986-y
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author Vaid, Neelam
Mishra, Prasun
Gokhale, Nikhil
Vaid, Sanjay
Vaze, Varada
Kothadiya, Ajay
Deka, Trisha
Agarwal, Rashmi
author_facet Vaid, Neelam
Mishra, Prasun
Gokhale, Nikhil
Vaid, Sanjay
Vaze, Varada
Kothadiya, Ajay
Deka, Trisha
Agarwal, Rashmi
author_sort Vaid, Neelam
collection PubMed
description Mucormycosis is an opportunistic fungal infection. India faced an unprecedented increase in patients with post coronavirus disease 2019 (COVID-19) associated rhino-orbito-cerebral mucormycosis (ROCM). This study proposes a grading system which correlates the extent of the disease with the management plan. An observational study was conducted January 2021–June 2021. We identified 65 patients. Eleven patients had mild disease, 27 patients had moderate, 16 patients were severe and 11 patients were graded as very severe. The management was planned based on this grading system. Early diagnosis, aggressive surgical debridement and antifungal drug therapy is the key to improve survival in ROCM. Procedures such as endoscopic orbital clearance, sublabial maxillectomy, and modified endoscopic Denkers (MED) approach facilitate access and surgical debridement. The new grading system proposed assists in planning the approach and extent of surgical debridement.
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spelling pubmed-85914272021-11-15 A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center Vaid, Neelam Mishra, Prasun Gokhale, Nikhil Vaid, Sanjay Vaze, Varada Kothadiya, Ajay Deka, Trisha Agarwal, Rashmi Indian J Otolaryngol Head Neck Surg Original Article Mucormycosis is an opportunistic fungal infection. India faced an unprecedented increase in patients with post coronavirus disease 2019 (COVID-19) associated rhino-orbito-cerebral mucormycosis (ROCM). This study proposes a grading system which correlates the extent of the disease with the management plan. An observational study was conducted January 2021–June 2021. We identified 65 patients. Eleven patients had mild disease, 27 patients had moderate, 16 patients were severe and 11 patients were graded as very severe. The management was planned based on this grading system. Early diagnosis, aggressive surgical debridement and antifungal drug therapy is the key to improve survival in ROCM. Procedures such as endoscopic orbital clearance, sublabial maxillectomy, and modified endoscopic Denkers (MED) approach facilitate access and surgical debridement. The new grading system proposed assists in planning the approach and extent of surgical debridement. Springer India 2021-11-15 2022-10 /pmc/articles/PMC8591427/ /pubmed/34804905 http://dx.doi.org/10.1007/s12070-021-02986-y Text en © Association of Otolaryngologists of India 2021
spellingShingle Original Article
Vaid, Neelam
Mishra, Prasun
Gokhale, Nikhil
Vaid, Sanjay
Vaze, Varada
Kothadiya, Ajay
Deka, Trisha
Agarwal, Rashmi
A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center
title A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center
title_full A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center
title_fullStr A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center
title_full_unstemmed A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center
title_short A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center
title_sort proposed grading system and experience of covid-19 associated rhino orbito cerebral mucormycosis from an indian tertiary care center
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591427/
https://www.ncbi.nlm.nih.gov/pubmed/34804905
http://dx.doi.org/10.1007/s12070-021-02986-y
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