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A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center
Mucormycosis is an opportunistic fungal infection. India faced an unprecedented increase in patients with post coronavirus disease 2019 (COVID-19) associated rhino-orbito-cerebral mucormycosis (ROCM). This study proposes a grading system which correlates the extent of the disease with the management...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer India
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591427/ https://www.ncbi.nlm.nih.gov/pubmed/34804905 http://dx.doi.org/10.1007/s12070-021-02986-y |
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author | Vaid, Neelam Mishra, Prasun Gokhale, Nikhil Vaid, Sanjay Vaze, Varada Kothadiya, Ajay Deka, Trisha Agarwal, Rashmi |
author_facet | Vaid, Neelam Mishra, Prasun Gokhale, Nikhil Vaid, Sanjay Vaze, Varada Kothadiya, Ajay Deka, Trisha Agarwal, Rashmi |
author_sort | Vaid, Neelam |
collection | PubMed |
description | Mucormycosis is an opportunistic fungal infection. India faced an unprecedented increase in patients with post coronavirus disease 2019 (COVID-19) associated rhino-orbito-cerebral mucormycosis (ROCM). This study proposes a grading system which correlates the extent of the disease with the management plan. An observational study was conducted January 2021–June 2021. We identified 65 patients. Eleven patients had mild disease, 27 patients had moderate, 16 patients were severe and 11 patients were graded as very severe. The management was planned based on this grading system. Early diagnosis, aggressive surgical debridement and antifungal drug therapy is the key to improve survival in ROCM. Procedures such as endoscopic orbital clearance, sublabial maxillectomy, and modified endoscopic Denkers (MED) approach facilitate access and surgical debridement. The new grading system proposed assists in planning the approach and extent of surgical debridement. |
format | Online Article Text |
id | pubmed-8591427 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer India |
record_format | MEDLINE/PubMed |
spelling | pubmed-85914272021-11-15 A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center Vaid, Neelam Mishra, Prasun Gokhale, Nikhil Vaid, Sanjay Vaze, Varada Kothadiya, Ajay Deka, Trisha Agarwal, Rashmi Indian J Otolaryngol Head Neck Surg Original Article Mucormycosis is an opportunistic fungal infection. India faced an unprecedented increase in patients with post coronavirus disease 2019 (COVID-19) associated rhino-orbito-cerebral mucormycosis (ROCM). This study proposes a grading system which correlates the extent of the disease with the management plan. An observational study was conducted January 2021–June 2021. We identified 65 patients. Eleven patients had mild disease, 27 patients had moderate, 16 patients were severe and 11 patients were graded as very severe. The management was planned based on this grading system. Early diagnosis, aggressive surgical debridement and antifungal drug therapy is the key to improve survival in ROCM. Procedures such as endoscopic orbital clearance, sublabial maxillectomy, and modified endoscopic Denkers (MED) approach facilitate access and surgical debridement. The new grading system proposed assists in planning the approach and extent of surgical debridement. Springer India 2021-11-15 2022-10 /pmc/articles/PMC8591427/ /pubmed/34804905 http://dx.doi.org/10.1007/s12070-021-02986-y Text en © Association of Otolaryngologists of India 2021 |
spellingShingle | Original Article Vaid, Neelam Mishra, Prasun Gokhale, Nikhil Vaid, Sanjay Vaze, Varada Kothadiya, Ajay Deka, Trisha Agarwal, Rashmi A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center |
title | A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center |
title_full | A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center |
title_fullStr | A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center |
title_full_unstemmed | A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center |
title_short | A Proposed Grading System and Experience of COVID-19 Associated Rhino Orbito Cerebral Mucormycosis from an Indian Tertiary Care Center |
title_sort | proposed grading system and experience of covid-19 associated rhino orbito cerebral mucormycosis from an indian tertiary care center |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591427/ https://www.ncbi.nlm.nih.gov/pubmed/34804905 http://dx.doi.org/10.1007/s12070-021-02986-y |
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