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Research Note: Morphology and immune function development of the jejunum and ileum in squab pigeons (Columba livia)

The study was aimed to evaluate the morphology and immune function development of the jejunum and ileum in squab pigeons (Columba livia), by determining the villus ultrastructure, secretory IgA, and cytokines. Eight squabs were randomly selected and sampled on the day of hatch (DOH), d 7 (D 7), 14 (...

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Autores principales: Xu, Qianqian, Miao, Sasa, Jian, Huafeng, Zou, Xiaoting, Dong, Xinyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591510/
https://www.ncbi.nlm.nih.gov/pubmed/34784512
http://dx.doi.org/10.1016/j.psj.2021.101529
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author Xu, Qianqian
Miao, Sasa
Jian, Huafeng
Zou, Xiaoting
Dong, Xinyang
author_facet Xu, Qianqian
Miao, Sasa
Jian, Huafeng
Zou, Xiaoting
Dong, Xinyang
author_sort Xu, Qianqian
collection PubMed
description The study was aimed to evaluate the morphology and immune function development of the jejunum and ileum in squab pigeons (Columba livia), by determining the villus ultrastructure, secretory IgA, and cytokines. Eight squabs were randomly selected and sampled on the day of hatch (DOH), d 7 (D 7), 14 (D 14), and 21 (D 21) post-hatch, respectively. The results showed that under transmission electron microscope, the enterocyte circumference in jejunum and ileum decreased with age. The tight junction involved in enterocyte circumference of jejunal villi plateaued from D 7, whereas that of ileal villi changed irregularly. The microvilli of jejunal and ileal villi was maximum at D 14. Under scanning electron microscope, the villus morphology of jejunum and ileum appeared finger-shaped at DOH. After D 7, the jejunal villi were still finger-shaped whereas the ileal villi were leaflike. The secretory IgA in jejunum was significantly increased at D 21. The TGF-β decreased linearly in jejunum and ileum. The anti-inflammatory cytokines increased linearly and proinflammatory cytokines decreased linearly in jejunum and ileum with age. In conclusion, the morphological changes of jejunal epithelium were concentrated at DOH–D 7 and ileal epithelium at DOH–D 14 mainly. The changes in mucus layer and immune-related factors of jejunum and ileum persisted for almost the entire period.
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spelling pubmed-85915102021-11-22 Research Note: Morphology and immune function development of the jejunum and ileum in squab pigeons (Columba livia) Xu, Qianqian Miao, Sasa Jian, Huafeng Zou, Xiaoting Dong, Xinyang Poult Sci METABOLISM AND NUTRITION The study was aimed to evaluate the morphology and immune function development of the jejunum and ileum in squab pigeons (Columba livia), by determining the villus ultrastructure, secretory IgA, and cytokines. Eight squabs were randomly selected and sampled on the day of hatch (DOH), d 7 (D 7), 14 (D 14), and 21 (D 21) post-hatch, respectively. The results showed that under transmission electron microscope, the enterocyte circumference in jejunum and ileum decreased with age. The tight junction involved in enterocyte circumference of jejunal villi plateaued from D 7, whereas that of ileal villi changed irregularly. The microvilli of jejunal and ileal villi was maximum at D 14. Under scanning electron microscope, the villus morphology of jejunum and ileum appeared finger-shaped at DOH. After D 7, the jejunal villi were still finger-shaped whereas the ileal villi were leaflike. The secretory IgA in jejunum was significantly increased at D 21. The TGF-β decreased linearly in jejunum and ileum. The anti-inflammatory cytokines increased linearly and proinflammatory cytokines decreased linearly in jejunum and ileum with age. In conclusion, the morphological changes of jejunal epithelium were concentrated at DOH–D 7 and ileal epithelium at DOH–D 14 mainly. The changes in mucus layer and immune-related factors of jejunum and ileum persisted for almost the entire period. Elsevier 2021-10-13 /pmc/articles/PMC8591510/ /pubmed/34784512 http://dx.doi.org/10.1016/j.psj.2021.101529 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle METABOLISM AND NUTRITION
Xu, Qianqian
Miao, Sasa
Jian, Huafeng
Zou, Xiaoting
Dong, Xinyang
Research Note: Morphology and immune function development of the jejunum and ileum in squab pigeons (Columba livia)
title Research Note: Morphology and immune function development of the jejunum and ileum in squab pigeons (Columba livia)
title_full Research Note: Morphology and immune function development of the jejunum and ileum in squab pigeons (Columba livia)
title_fullStr Research Note: Morphology and immune function development of the jejunum and ileum in squab pigeons (Columba livia)
title_full_unstemmed Research Note: Morphology and immune function development of the jejunum and ileum in squab pigeons (Columba livia)
title_short Research Note: Morphology and immune function development of the jejunum and ileum in squab pigeons (Columba livia)
title_sort research note: morphology and immune function development of the jejunum and ileum in squab pigeons (columba livia)
topic METABOLISM AND NUTRITION
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591510/
https://www.ncbi.nlm.nih.gov/pubmed/34784512
http://dx.doi.org/10.1016/j.psj.2021.101529
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