Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi

Vesicle formation at endomembranes requires the selective concentration of cargo by coat proteins. Conserved adapter protein complexes at the Golgi (AP-3), the endosome (AP-1), or the plasma membrane (AP-2) with their conserved core domain and flexible ear domains mediate this function. These comple...

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Detalles Bibliográficos
Autores principales: Schoppe, Jannis, Schubert, Evelyn, Apelbaum, Amir, Yavavli, Erdal, Birkholz, Oliver, Stephanowitz, Heike, Han, Yaping, Perz, Angela, Hofnagel, Oliver, Liu, Fan, Piehler, Jacob, Raunser, Stefan, Ungermann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591511/
https://www.ncbi.nlm.nih.gov/pubmed/34688652
http://dx.doi.org/10.1016/j.jbc.2021.101334

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