DNA hypomethylation leads to cGAS‐induced autoinflammation in the epidermis

DNA methylation is a fundamental epigenetic modification, important across biological processes. The maintenance methyltransferase DNMT1 is essential for lineage differentiation during development, but its functions in tissue homeostasis are incompletely understood. We show that epidermis‐specific D...

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Detalles Bibliográficos
Autores principales: Beck, Mirjam A, Fischer, Heinz, Grabner, Lisa M, Groffics, Tamara, Winter, Mircea, Tangermann, Simone, Meischel, Tina, Zaussinger‐Haas, Barbara, Wagner, Patrick, Fischer, Carina, Folie, Christina, Arand, Julia, Schöfer, Christian, Ramsahoye, Bernard, Lagger, Sabine, Machat, Georg, Eisenwort, Gregor, Schneider, Stephanie, Podhornik, Alexandra, Kothmayer, Michael, Reichart, Ursula, Glösmann, Martin, Tamir, Ido, Mildner, Michael, Sheibani‐Tezerji, Raheleh, Kenner, Lukas, Petzelbauer, Peter, Egger, Gerda, Sibilia, Maria, Ablasser, Andrea, Seiser, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591534/
https://www.ncbi.nlm.nih.gov/pubmed/34586646
http://dx.doi.org/10.15252/embj.2021108234

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