TORREY, a Phase 2 study to evaluate the efficacy and safety of inhaled seralutinib for the treatment of pulmonary arterial hypertension

Aberrant kinase signaling that involves platelet-derived growth factor receptor (PDGFR) α/β, colony stimulating factor 1 receptor (CSF1R), and stem cell factor receptor (c-KIT) pathways may be responsible for vascular remodeling in pulmonary arterial hypertension. Targeting these specific pathways m...

Descripción completa

Detalles Bibliográficos
Autores principales: Frantz, Robert P., Benza, Raymond L., Channick, Richard N., Chin, Kelly, Howard, Luke S., McLaughlin, Vallerie V., Sitbon, Olivier, Zamanian, Roham T., Hemnes, Anna R., Cravets, Matt, Bruey, Jean-Marie, Roscigno, Robert, Mottola, David, Elman, Erin, Zisman, Lawrence S., Ghofrani, Hossein-Ardeschir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591655/
https://www.ncbi.nlm.nih.gov/pubmed/34790348
http://dx.doi.org/10.1177/20458940211057071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591655/
https://www.ncbi.nlm.nih.gov/pubmed/34790348
http://dx.doi.org/10.1177/20458940211057071

Ejemplares similares