Cargando…
The terpenes camphene and alpha-bisabolol inhibit inflammatory and neuropathic pain via Cav3.2 T-type calcium channels
T-type calcium channels are known molecular targets of certain phytocannabinoids and endocannabinoids. Here we explored the modulation of Cav3.2 T-type calcium channels by terpenes derived from cannabis plants. A screen of eight commercially available terpenes revealed that camphene and alpha-bisabo...
Autores principales: | Gadotti, Vinicius M., Huang, Sun, Zamponi, Gerald W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591808/ https://www.ncbi.nlm.nih.gov/pubmed/34775970 http://dx.doi.org/10.1186/s13041-021-00876-6 |
Ejemplares similares
-
NMP-7 inhibits chronic inflammatory and neuropathic pain via block of Cav3.2 T-type calcium channels and activation of CB2 receptors
por: Berger, N Daniel, et al.
Publicado: (2014) -
Analgesia by intrathecal delta-9-tetrahydrocannabinol is dependent on Cav3.2 calcium channels
por: Gadotti, Vinicius de Maria, et al.
Publicado: (2023) -
Cav3.2 T-type calcium channels control acute itch in mice
por: Gadotti, Vinicius M., et al.
Publicado: (2020) -
Antihyperalgesic effect of joint mobilization requires Cav3.2 calcium channels
por: Martins, Daniel F., et al.
Publicado: (2023) -
Small organic molecule disruptors of Cav3.2 - USP5 interactions reverse inflammatory and neuropathic pain
por: Gadotti, Vinicius M, et al.
Publicado: (2015)