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The simple observational critical care studies: estimations by students, nurses, and physicians of in-hospital and 6-month mortality

BACKGROUND: Prognostic assessments of the mortality of critically ill patients are frequently performed in daily clinical practice and provide prognostic guidance in treatment decisions. In contrast to several sophisticated tools, prognostic estimations made by healthcare providers are always availa...

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Autores principales: Cox, Eline G. M., Onrust, Marisa, Vos, Madelon E., Paans, Wolter, Dieperink, Willem, Koeze, Jacqueline, van der Horst, Iwan C. C., Wiersema, Renske
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591867/
https://www.ncbi.nlm.nih.gov/pubmed/34782000
http://dx.doi.org/10.1186/s13054-021-03809-w
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author Cox, Eline G. M.
Onrust, Marisa
Vos, Madelon E.
Paans, Wolter
Dieperink, Willem
Koeze, Jacqueline
van der Horst, Iwan C. C.
Wiersema, Renske
author_facet Cox, Eline G. M.
Onrust, Marisa
Vos, Madelon E.
Paans, Wolter
Dieperink, Willem
Koeze, Jacqueline
van der Horst, Iwan C. C.
Wiersema, Renske
author_sort Cox, Eline G. M.
collection PubMed
description BACKGROUND: Prognostic assessments of the mortality of critically ill patients are frequently performed in daily clinical practice and provide prognostic guidance in treatment decisions. In contrast to several sophisticated tools, prognostic estimations made by healthcare providers are always available and accessible, are performed daily, and might have an additive value to guide clinical decision-making. The aim of this study was to evaluate the accuracy of students’, nurses’, and physicians’ estimations and the association of their combined estimations with in-hospital mortality and 6-month follow-up. METHODS: The Simple Observational Critical Care Studies is a prospective observational single-center study in a tertiary teaching hospital in the Netherlands. All patients acutely admitted to the intensive care unit were included. Within 3 h of admission to the intensive care unit, a medical or nursing student, a nurse, and a physician independently predicted in-hospital and 6-month mortality. Logistic regression was used to assess the associations between predictions and the actual outcome; the area under the receiver operating characteristics (AUROC) was calculated to estimate the discriminative accuracy of the students, nurses, and physicians. RESULTS: In 827 out of 1,010 patients, in-hospital mortality rates were predicted to be 11%, 15%, and 17% by medical students, nurses, and physicians, respectively. The estimations of students, nurses, and physicians were all associated with in-hospital mortality (OR 5.8, 95% CI [3.7, 9.2], OR 4.7, 95% CI [3.0, 7.3], and OR 7.7 95% CI [4.7, 12.8], respectively). Discriminative accuracy was moderate for all students, nurses, and physicians (between 0.58 and 0.68). When more estimations were of non-survival, the odds of non-survival increased (OR 2.4 95% CI [1.9, 3.1]) per additional estimate, AUROC 0.70 (0.65, 0.76). For 6-month mortality predictions, similar results were observed. CONCLUSIONS: Based on the initial examination, students, nurses, and physicians can only moderately predict in-hospital and 6-month mortality in critically ill patients. Combined estimations led to more accurate predictions and may serve as an example of the benefit of multidisciplinary clinical care and future research efforts. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13054-021-03809-w.
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spelling pubmed-85918672021-11-15 The simple observational critical care studies: estimations by students, nurses, and physicians of in-hospital and 6-month mortality Cox, Eline G. M. Onrust, Marisa Vos, Madelon E. Paans, Wolter Dieperink, Willem Koeze, Jacqueline van der Horst, Iwan C. C. Wiersema, Renske Crit Care Research BACKGROUND: Prognostic assessments of the mortality of critically ill patients are frequently performed in daily clinical practice and provide prognostic guidance in treatment decisions. In contrast to several sophisticated tools, prognostic estimations made by healthcare providers are always available and accessible, are performed daily, and might have an additive value to guide clinical decision-making. The aim of this study was to evaluate the accuracy of students’, nurses’, and physicians’ estimations and the association of their combined estimations with in-hospital mortality and 6-month follow-up. METHODS: The Simple Observational Critical Care Studies is a prospective observational single-center study in a tertiary teaching hospital in the Netherlands. All patients acutely admitted to the intensive care unit were included. Within 3 h of admission to the intensive care unit, a medical or nursing student, a nurse, and a physician independently predicted in-hospital and 6-month mortality. Logistic regression was used to assess the associations between predictions and the actual outcome; the area under the receiver operating characteristics (AUROC) was calculated to estimate the discriminative accuracy of the students, nurses, and physicians. RESULTS: In 827 out of 1,010 patients, in-hospital mortality rates were predicted to be 11%, 15%, and 17% by medical students, nurses, and physicians, respectively. The estimations of students, nurses, and physicians were all associated with in-hospital mortality (OR 5.8, 95% CI [3.7, 9.2], OR 4.7, 95% CI [3.0, 7.3], and OR 7.7 95% CI [4.7, 12.8], respectively). Discriminative accuracy was moderate for all students, nurses, and physicians (between 0.58 and 0.68). When more estimations were of non-survival, the odds of non-survival increased (OR 2.4 95% CI [1.9, 3.1]) per additional estimate, AUROC 0.70 (0.65, 0.76). For 6-month mortality predictions, similar results were observed. CONCLUSIONS: Based on the initial examination, students, nurses, and physicians can only moderately predict in-hospital and 6-month mortality in critically ill patients. Combined estimations led to more accurate predictions and may serve as an example of the benefit of multidisciplinary clinical care and future research efforts. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13054-021-03809-w. BioMed Central 2021-11-15 /pmc/articles/PMC8591867/ /pubmed/34782000 http://dx.doi.org/10.1186/s13054-021-03809-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Cox, Eline G. M.
Onrust, Marisa
Vos, Madelon E.
Paans, Wolter
Dieperink, Willem
Koeze, Jacqueline
van der Horst, Iwan C. C.
Wiersema, Renske
The simple observational critical care studies: estimations by students, nurses, and physicians of in-hospital and 6-month mortality
title The simple observational critical care studies: estimations by students, nurses, and physicians of in-hospital and 6-month mortality
title_full The simple observational critical care studies: estimations by students, nurses, and physicians of in-hospital and 6-month mortality
title_fullStr The simple observational critical care studies: estimations by students, nurses, and physicians of in-hospital and 6-month mortality
title_full_unstemmed The simple observational critical care studies: estimations by students, nurses, and physicians of in-hospital and 6-month mortality
title_short The simple observational critical care studies: estimations by students, nurses, and physicians of in-hospital and 6-month mortality
title_sort simple observational critical care studies: estimations by students, nurses, and physicians of in-hospital and 6-month mortality
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591867/
https://www.ncbi.nlm.nih.gov/pubmed/34782000
http://dx.doi.org/10.1186/s13054-021-03809-w
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