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Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study

Necrotizing enterocolitis (NEC) is a typical disorder of preterm newborns, with a high mortality and morbidity rate. The therapeutic and nutritional management of disease depends on several factors. Its prognosis is linked, in addition to the severity of the disease and the need for surgery, to a co...

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Autores principales: Savarino, Giovanni, Carta, Maurizio, Cimador, Marcello, Corsello, Antonio, Giuffrè, Mario, Schierz, Ingrid Anne Mandy, Serra, Gregorio, Corsello, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591939/
https://www.ncbi.nlm.nih.gov/pubmed/34775993
http://dx.doi.org/10.1186/s13052-021-01180-8
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author Savarino, Giovanni
Carta, Maurizio
Cimador, Marcello
Corsello, Antonio
Giuffrè, Mario
Schierz, Ingrid Anne Mandy
Serra, Gregorio
Corsello, Giovanni
author_facet Savarino, Giovanni
Carta, Maurizio
Cimador, Marcello
Corsello, Antonio
Giuffrè, Mario
Schierz, Ingrid Anne Mandy
Serra, Gregorio
Corsello, Giovanni
author_sort Savarino, Giovanni
collection PubMed
description Necrotizing enterocolitis (NEC) is a typical disorder of preterm newborns, with a high mortality and morbidity rate. The therapeutic and nutritional management of disease depends on several factors. Its prognosis is linked, in addition to the severity of the disease and the need for surgery, to a correct enteral feeding in these patients. This study aims to identify the clinical characteristics of 18 patients with NEC, evaluating the different therapeutic paths undertaken, the type of formula used and the survival rate of this population. Average time of enteral nutrition before the NEC onset was 11,3 ± 11,6 days, with an average fasting period since the onset of 24 ± 18.9 days. 77.8% of patients received surgery and resumed enteral nutrition 17.7 ± 17.9 days after the intervention. The overall survival rate of our cohort was 55.5%. More prospective studies are needed to evaluate the long-term outcomes of survived children with NEC.
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spelling pubmed-85919392021-11-15 Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study Savarino, Giovanni Carta, Maurizio Cimador, Marcello Corsello, Antonio Giuffrè, Mario Schierz, Ingrid Anne Mandy Serra, Gregorio Corsello, Giovanni Ital J Pediatr Research Necrotizing enterocolitis (NEC) is a typical disorder of preterm newborns, with a high mortality and morbidity rate. The therapeutic and nutritional management of disease depends on several factors. Its prognosis is linked, in addition to the severity of the disease and the need for surgery, to a correct enteral feeding in these patients. This study aims to identify the clinical characteristics of 18 patients with NEC, evaluating the different therapeutic paths undertaken, the type of formula used and the survival rate of this population. Average time of enteral nutrition before the NEC onset was 11,3 ± 11,6 days, with an average fasting period since the onset of 24 ± 18.9 days. 77.8% of patients received surgery and resumed enteral nutrition 17.7 ± 17.9 days after the intervention. The overall survival rate of our cohort was 55.5%. More prospective studies are needed to evaluate the long-term outcomes of survived children with NEC. BioMed Central 2021-11-14 /pmc/articles/PMC8591939/ /pubmed/34775993 http://dx.doi.org/10.1186/s13052-021-01180-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Savarino, Giovanni
Carta, Maurizio
Cimador, Marcello
Corsello, Antonio
Giuffrè, Mario
Schierz, Ingrid Anne Mandy
Serra, Gregorio
Corsello, Giovanni
Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study
title Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study
title_full Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study
title_fullStr Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study
title_full_unstemmed Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study
title_short Necrotizing enterocolitis in the preterm: newborns medical and nutritional Management in a Single-Center Study
title_sort necrotizing enterocolitis in the preterm: newborns medical and nutritional management in a single-center study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591939/
https://www.ncbi.nlm.nih.gov/pubmed/34775993
http://dx.doi.org/10.1186/s13052-021-01180-8
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